117156-31-7

Basic information

• Product Name: (S)-2-Isocyanato-3-phenyl-propionic acid tert-butyl ester
• Synonyms: (S)-2-Isocyanato-3-phenyl-propionic acid tert-butyl ester
• CAS NO: 117156-31-7
• Molecular Weight: 247.294
• Mol File: 117156-31-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (S)-2-Isocyanato-3-phenyl-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Isocyanato-3-phenyl-propionic acid tert-butyl ester(117156-31-7)
• EPA Substance Registry System: (S)-2-Isocyanato-3-phenyl-propionic acid tert-butyl ester(117156-31-7)

Safety Data

• Hazardous Substances Data: 117156-31-7(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 16874-17-2 L-phenylalanine tert-butyl ester 
• 75-44-5 phosgene 
• 15100-75-1 L-phenylalanine tert-butyl ester hydrochloride 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 1416343-02-6 N-(N-fluorenylidene-2-aza-glycinyl)-L-phenylalanine tert-butyl ester 
• 1416343-04-8 N-(N-fluorenylidene-2-aza-2-propargylglycinyl)-L-phenylalanine tert-butyl ester 
• 1432474-23-1 C₃₆H₃₇NO₁₅ 
• 1432474-28-6 C₃₂H₂₉NO₁₅ 

Relevant articles and documents

Conjugates of Tetramethylpyrazine’ metabolites and amino acid as potential antiplatelet agents

Tetramethylpyrazine (TMP) is commonly used as an antiplatelet drug in clinic. However, the short half-life and low bioavailability limited its applications. 3, 5, 6-Trimethylpyrazine-2-carboxAylic acid (TMP-COOH) and 2-hydroxy-3, 5, 6-trimethylpyrazine (T

Synthesis and physiochemical property evaluation of carbamate derivatives of scutellarin methyl ester

A series of carbamate prodrugs of scutellarin methyl ester (4a-4e) were prepared in the presence of bis(trichloromethyl) carbonate (BTC) with scutellarin methyl esters and l-amino acid tert-butyl ester hydrochloride as starting materials. In vitro stability and aqueous solubility of target compounds were evaluated. The results indicated that compounds 4d and 4e have higher solubility and in vitro stability than scutellarin respectively.

Isocyanates, Part 4.10 Convenient Phosgene-Free Method for the Synthesis and Derivatization of Enantiopure α-Isocyanato Carboxylic Acid Esters

A novel phosgene-free procedure for the synthesis of α-isocyanato carboxylic acid esters starting from α-amino acid esters has been achieved. The isocyanates are obtained enantiomerically pure (> 99% ee) by a DMAP-catalyzed isocyanation with di-tert-butyl