117161-88-3

Upstream product

• 55740-07-3 (4S)-4-benzyl-5-oxo-1,3-oxazolidine-3-carboxylic acid benzyl ester 
• 106-95-6 allyl bromide 
• 851234-20-3 (R)-4-Benzyl-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 1161-13-3 N-Cbz-L-Phe 

Downstream Products

• 117161-89-4 (2R,S)-methyl 2-<(benzyloxycarbonyl)amino>-2-(phenylmethyl)pent-4-enoate 
• 117162-01-3 (4S,R)-3-(benzyloxycarbonyl)-4-(phenylmethyl)-4-<1-(3-hydroxypropyl)>-5-oxooxazolidine 
• 143140-28-7 4-Benzyl-5-oxo-4-(2-oxo-ethyl)-oxazolidine-3-carboxylic acid benzyl ester 
• 143140-29-8 (R)-6-Benzyl-6-benzyloxycarbonylamino-5-oxo-hexahydro-pyrrolo[2,1-b]thiazole-3-carboxylic acid methyl ester 
• 117162-22-8 methyl <2(S)-<3-<(benzyloxycarbonyl)amino>-3-(phenylmethyl)-2-oxo-1-piperidinyl>-3-phenylpropionyl>-L-phenylalaninate 
• 117162-21-7 methyl <2(S)-<3-<(benzyloxycarbonyl)amino>-3-(phenylmethyl)-2-oxo-1-pyrrolidinyl>-3-phenylpropionyl>-L-phenylalaninate 
• 117162-24-0 (2S)-methyl 2-<3-<amino>-3-(phenylmethyl)-2-oxo-1-piperidinyl>-3-phenylpropionate 
• 117162-23-9 (2S)-methyl 2-<3-<amino>-3-(phenylmethyl)-2-oxo-1-pyrrolidinyl>-3-phenylpropionate 
• 117162-05-7 4-Benzyl-4-{3-[(S)-2-(1H-imidazol-4-yl)-1-methoxycarbonyl-ethylamino]-propyl}-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 117162-04-6 4-Benzyl-4-[3-((S)-1-methoxycarbonyl-2-phenyl-ethylamino)-propyl]-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 117161-93-0 2-Benzyl-2-benzyloxycarbonylamino-4-[(S)-2-(1H-imidazol-4-yl)-1-methoxycarbonyl-ethylamino]-butyric acid methyl ester 
• 117161-92-9 2-Benzyl-2-benzyloxycarbonylamino-4-((S)-1-methoxycarbonyl-2-phenyl-ethylamino)-butyric acid methyl ester 
• 117162-15-9 (2S)-methyl 2-<3-<(benzyloxycarbonyl)amino>-3-(phenylmethyl)-2-oxo-1-piperidinyl>-3-(4-imidazolyl)propionate 
• 117162-10-4 (2S)-methyl 2-<3(R,S)-<(benzyloxycarbonyl)amino>-3-(phenylmethyl)-2-oxo-1-pyrrolidinyl>-3-(4-imidazolyl)propionate 

Relevant academic research and scientific papers

SYNTHESIS OF A BICYCLIC γ-LACTAM DIPEPTIDE ANALOGUE

The asymmetric synthesis of a bicyclic γ-lactam analogue of a dipeptide, in which the key step was the bis-alkylation of an optically active diphenyloxazinone chiral glycine anion equivalent is described.

Efficient and Versatile Synthesis of Dipeptide Isosteres Containing γ- or δ-Lactams

Independent five-step syntheses of γ- and δ-lactam-containing dipeptide isosteres, starting from the known compound, (4S)-3-(carbobenzyloxy)-4-(phenylmethyl)-5-oxooxazolidine (3), are reported.Alkylation of 3 with allyl bromide provided the corresponding