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117174-79-5

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117174-79-5 Usage

General Description

1-Benzoyl-3-(3,5-dimethylphenyl)thiourea, also known as 3,5-dimethylbenzoylthiourea, is a chemical compound with the molecular formula C16H16N2OS. It is a white crystalline powder that is used in pharmaceutical and chemical research. It has been investigated for its potential antiviral, antimicrobial, and antioxidant properties. Additionally, 1-Benzoyl-3-(3,5-dimethylphenyl)thiourea has been studied for its potential use in controlling the growth of certain types of cancer cells. 5-[(Benzoylcarbamothioyl)amino]-m-xylene is a chemical compound with the molecular formula C16H14N2OS. It is a yellowish brown powder that is used in the synthesis of various organic compounds. 1-Benzoyl-3-(3,5-dimethylphenyl)thiourea, 5-[(Benzoylcarbamothioyl)amino]-m-xylene has been studied for its potential use as a pesticide and for its effects on plant growth. Additionally, 5-[(Benzoylcarbamothioyl)amino]-m-xylene has been investigated for its potential antimicrobial and antitumor properties.

Check Digit Verification of cas no

The CAS Registry Mumber 117174-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,1,7 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 117174-79:
(8*1)+(7*1)+(6*7)+(5*1)+(4*7)+(3*4)+(2*7)+(1*9)=125
125 % 10 = 5
So 117174-79-5 is a valid CAS Registry Number.

117174-79-5Downstream Products

117174-79-5Relevant articles and documents

Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines

Gon?alves, Itamar Luís,Rockenbach, Liliana,Das Neves, Gustavo Machado,G?ethel, Gabriela,Nascimento, Fabiana,Porto Kagami, Luciano,Figueiró, Fabrício,Oliveira De Azambuja, Gabriel,De Fraga Dias, Amanda,Amaro, Andressa,De Souza, Lauro Mera,Da Rocha Pitta, Ivan,Avila, Daiana Silva,Kawano, Daniel Fábio,Garcia, Solange Cristina,Battastini, Ana Maria Oliveira,Eifler-Lima, Vera Lucia

, p. 995 - 1010 (2018/06/27)

An original and focused library of two sets of dihydropyrimidin-2-thiones (DHPMs) substituted with N-1 aryl groups derived from monastrol was designed and synthesized in order to discover a more effective Eg5 ligand than the template. Based on molecular docking studies, four ligands were selected to perform pharmacological investigations against two glioma cell lines. The results led to the discovery of two original compounds, called 20h and 20e, with an anti-proliferative effects, achieving IC50 values of about half that of the IC50 of monastrol in both cell lines. As with monastrol, flow cytometry analyses showed that the 20e and 20h compounds induced cell cycle arrest in the G2/M phase, and immunocytochemistry essays revealed the formation of monopolar spindles due to Eg5 inhibition without any toxicity to Caenorhabditis elegans.

COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING HYPERPROLIFERATIVE DISEASES

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Page/Page column 43; 44, (2014/10/04)

Coumarin derivative compounds and methods for the treatment of hyperproliferative diseases, such as cancer, polycystic kidney disease, and fibrosis of different tissues (e.g., idiopathic pulmonary fibrosis), are provided. The methods include administering

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