117187-08-3

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 83791-32-6 N-carboxy dehydrophenylalanine anhydride 

Downstream Products

• 119767-94-1 Boc-A-(D)-L-ΔF-OMe 
• 117833-86-0 (E)-2-((R)-2-Amino-4-methyl-pentanoylamino)-3-phenyl-acrylic acid methyl ester 
• 119767-94-1 Boc-A-L-ΔF-OMe 
• 119767-94-1 Boc-(D)-A-L-ΔF-OMe 
• 117833-86-0 H-L-Leu-(Z)-ΔPhe-OMe 
• 119767-96-3 Boc-L-ΔF-(D)-A-OMe 

Relevant academic research and scientific papers

Syntheses and Separations of Diastereomers of Protected-Δ1-, Δ2-, and Δ3-Dehydrotripeptides

Total eighteen kinds of Δ1-, Δ2-, and Δ3-dehydrotripeptides (DHP) containing of a ΔPhe and two chiral α-amino acid residues were synthesized and the diastereomeric mixture of DHP were subjected to the HPLC separation.From the results and the 1H NMR spectral data, it was found to be significant relationship between the separation and the conformational structure of DHP.

FACILE SYNTHESIS OF FOUR ISOMERS OF LINEAR TENTOXIN SEQUENCE BY USING N-CARBOXY DEHYDROPHENYLALANINE ANHYDRIDE

Four isomers of protected dehydrotetrapeptides of linear tentoxin sequence, consisted of Gly, Ala, Leu, and ΔPhe residues, were readily synthesized by using N-carboxy dehydrophenylalanine anhydride.