1171875-24-3Relevant academic research and scientific papers
First total synthesis of (+)-11-hydroxyerythratidine
Onoda, Toshio,Takikawa, Yosuke,Fujimoto, Takashi,Yasui, Yoshizumi,Suzuki, Keisuke,Matsumoto, Takashi
scheme or table, p. 1041 - 1046 (2009/09/30)
The first total synthesis of (+)-11-hydroxyerythratidine is described. The strategy is featured by a highly stereoselective construction of the C(5) spiro center via the Lewis acid promoted cyclization of ortho-quinone acetal, derived from di-ortho-substituted biphenyl 9 with a chiral center at the side chain. Georg Thieme Verlag Stuttgart.
