117237-13-5Relevant academic research and scientific papers
2-Arylamino-3-cyano-5,6,7,8-tetrahydroquinolines and 2-Substituted 1-Aryl-6,7,8,9-Tetrahydropyrimidoquinolin-4-ones Derived Therefrom
Gavrilov, M. Yu.,Konshin, M. E.
, p. 71 - 73 (2007/10/02)
Reaction of 2-chloro-3-cyano-5,6,7,8-tetrahydroquinoline with arylamines gives 2-arylamino-3-cyano-5,6,7,8-tetrahydroquinolines, which on reaction with acetic anhydride or benzoyl chloride are converted into the N-acyl derivatives, and on further treatment with hydrogen chloride in anhydrous ethanol, into 2-substituted 1-aryl-6,7,8,9-tetrahydropyrimidoquinolin-4-ones.
