65242-27-5

Usage

Uses

Used in Pharmaceutical Industry:
2-CHLORO-5,6,7,8-TETRAHYDROQUINOLINE-3-CARBONITRILE is used as a building block for the synthesis of various biologically active compounds due to its unique chemical structure and reactivity. It plays a crucial role in the development of complex pharmaceutical compounds, contributing to the advancement of new drug therapies.
Used in Research and Development:
In the field of organic synthesis and medicinal chemistry, 2-CHLORO-5,6,7,8-TETRAHYDROQUINOLINE-3-CARBONITRILE is utilized as a research chemical. Its properties are studied to understand its potential applications and to develop new methods for synthesizing related compounds, thereby expanding the scope of chemical research and innovation in medicinal applications.

InChI:InChI=1/C10H9ClN2/c11-10-8(6-12)5-7-3-1-2-4-9(7)13-10/h5H,1-4H2

Upstream product

• 108-94-1 cyclohexanone 
• 4241-13-8 2-oxo-1,2,5,6,7,8-hexahydro-3-quinoline-3-carbonitrile 

Downstream Products

• 65242-28-6 2-bromo-5,6,7,8-tetrahydro-3-quinolinecarbonitrile 
• 117237-23-7 1-(4-Methoxy-phenyl)-2-methyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-21-5 2-Methyl-1-o-tolyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-20-4 2-Methyl-1-p-tolyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-22-6 2-Methyl-1-m-tolyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-19-1 2-Methyl-1-phenyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-17-9 N-benzoyl-2-anilino-3-cyano-5,6,7,8-tetrahydroquinoline 
• 117237-24-8 1,2-Diphenyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-one 
• 117237-16-8 N-(3-Cyano-5,6,7,8-tetrahydro-quinolin-2-yl)-N-(4-methoxy-phenyl)-acetamide 

Relevant academic research and scientific papers

Synthesis and Neurotropic Activity of New Pyrimido[4′,5′:4,5]Thieno[2,3-b]Quinoline Derivatives

New methods for preparing pyrimido[4′,5′:4,5]thieno[2,3-b]quinoline derivatives based on 3-cyanohexahydro-2-quinoline were developed. The neurotropic activity of these compounds was studied.

Synthesis of 3-Amino-2-carboxamide Tetrahydropyrrolo[2,3- b ]quinolines

This article communicates the first synthesis of 3-amino-2-carboxamide pyrrolo[2,3-b]quinolines and fused-ring pyrrolopyridines in an efficient synthesis via a Thorpe-Ziegler transformation. The reported synthetic route allows for a wide range of nitrogen analogues of thienopyridines - compounds which have potent bioactivities but poor aqueous solubility.

NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS

The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.