117238-34-3Relevant articles and documents
A NOVEL INHIBITOR OF HUMAN α-L-FUCOSIDASE: ENANTIOSELECTIVE SYNTHESIS OF L-FUCOAMIDRAZONE
Schedler, David J. A.,Bowen, Benjamin R.,Ganem, Bruce
, p. 3845 - 3848 (2007/10/02)
A short, chiral synthesis of the title inhibitor 1 is reported from D-galactosamine by chain end interchange.The L-fucoamidrazone is a good competitive inhibitor of human α-L-fucosidase (Ki = 820 nM).
δ-Lactams: Synthesis from D-glucose, and preliminary evaluation as a fucosidase inhibitor, of L-fuconic-δ-lactam
Fleet,Ramsden,Dwek,Rademacher,Fellows,Nash,Green,Winchester
, p. 483 - 485 (2007/10/02)
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