1172418-19-7Relevant articles and documents
Synthesis and antihepatotoxic activity of 2-(substituted-phenyl)-5-(2,3- dihydro-1,4-benzodioxane-2-yl)-1,3,4-oxadiazole derivatives
Ahmed, Bahar,Habibullah,Khan, Shamshir
, p. 216 - 221 (2011/10/18)
Novel 1,3,4-oxadizole derivatives containing the 1,4-dioxane ring system were synthesised starting from 2,3-dihydro-1,4-benzodioxane-2-carbohydrazide. The synthesised compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Some compounds demonstrated a significant antihepatotoxic activity comparable to the standard drug Silymarin.