1172607-38-3Relevant academic research and scientific papers
Three-component Nef-Huisgen access to 1,2,4-triazoles
El Kaim, Laurent,Grimaud, Laurence,Wagschal, Simon
, p. 1315 - 1317 (2009)
We present herein a new three-component triazole synthesis involving a Nef-Huisgen cascade. After the α-addition of acyl chlorides onto isocyanides (Nef reaction), the resulting imidoyl chloride is treated with tetrazoles under suitable activation (ZnCls
