117275-32-8

Upstream product

• 34246-23-6 benzyl D-glucopyranoside 
• 116-11-0 2-Methoxypropene 
• 15548-45-5 (2S,3S,4S,5S,6R)-2-benzyloxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol 
• 77-76-9 2,2-dimethoxy-propane 
• 100-51-6 benzyl alcohol 
• 1008130-95-7 C₁₄H₂₀Cl₃NO₆ 
• 4304-12-5 (2R,3R,4S,5S,6R)-2-(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 83-87-4 D-glucose pentaacetate 
• 10343-13-2 benzyl-2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 
• 530-26-7 D-Mannose 
• 335162-25-9 benzyl α,β-D-galactopyranoside 
• 2280-44-6 D-Glucose 

Downstream Products

• 139722-13-7 benzyl 2,3-O-isopropylidene-4,6-di-O-diphenoxyphosphoryl-α-D-mannopyranoside 
• 417711-25-2 benzyl 4-O-acetyl-2,3-di-O-benzoyl-6-deoxy-6-fluoro-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzoyl-α-D-mannopyranoside 
• 417711-26-3 4-O-acetyl-2,3-di-O-benzoyl-6-deoxy-6-fluoro-β-D-galactopyranosyl-(1->4)-2,3,6-tri-O-benzoyl-α-D-mannopyranose 
• 417711-24-1 benzyl 4-O-acetyl-2,3-di-O-benzoyl-6-deoxy-6-fluoro-β-D-galactopyranosyl-(1->4)-6-O-benzoyl-2,3-O-isopropylidene-α-D-mannopyranoside 
• 417711-23-0 benzyl 6-O-benzoyl-2,3-O-isopropylidene-α-D-mannopyranoside 
• 139722-12-6 benzyl 2,3-O-isopropylidene-α-D-mannopyranoside 

Relevant academic research and scientific papers

1,2-DIDEOXY-3,4:5,7-BIS-O-(1-METHYLETHYLIDENE)-D-GLUCO- AND D-GALACTO-HEPT-1-YNITOLS: SYNTHESIS AND CONFORMATIONAL STUDIES.

1,2-dideoxy-3,4:5,7-bis-O-(1-methylethylidene)-D-gluco- and D-galacto-hept-1-ynitols were synthesized starting respectively from benzyl α,β-D-glucopyranoside and from benzyl α,β-D-galactopyranoside by bis-acetonidation, hydrogenolysis, Wittig reaction wit

Using In(III) as a promoter for glycosylation

InCl3, InBr3, and In(OTf)3 were tested as promoters in the preparation of glycosides from trichloroacetimidate precursors. A range of protecting groups and of alcohol acceptors were used to determine the versatility of these promoters. Disaccharide formation was demonstrated. In most cases, the In(III) compounds were shown to promote glycosylation better than the widely used promoter BF3·OEt2.

Preventing protein oxidation with sugars: Scavenging of hypohalous acids by 5-selenopyranose and 4-selenofuranose derivatives

Heme peroxidases including myeloperoxidase (MPO) are released at sites of inflammation by activated leukocytes. MPO generates hypohalous acids (HOX, X = Cl, Br, SCN) from H2O2; these oxidants are bactericidal and are key components o

SELENO-COMPOUNDS AND THERAPEUTIC USES THEREOF

The present invention relates to compounds and compositions useful as antioxidants and in particular to selenium containing compounds of formula (I): wherein n is 1, 2, or 3; m is 2, 3, 4, or 5; and each R] is independently -(optionally substituted C 1 -C3 alkylene) p-OH, where p is 0 or 1, or a salt thereof. The invention also relates to the use of these seleno-compounds in the treatment of diseases or conditions associated with increased levels of oxidants produced by myeloperoxidase (MPO), such as for instance, atherosclerosis.

Cationic palladium(II)-catalyzed stereoselective glycosylation with glycosyl trichloroacetimidates

(Chemical Equation Presented) The development of a new method for stereoselective glycosylation with glycosyl trichloroacetimidate donors employing cationic palladium(II), Pd(CH3CN)4(BF 4)2, is described. This p

Parasite glycoconjugates. Part 12. Synthesis of deoxy, fluorodeoxy and aminodeoxy disaccharide phosphates, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania

A set of phosphodisaccharides, structural analogues of the β-D-galactosyl-(1→4)-α-D-mannosyl phosphate 1, are synthesized using the Koenigs-Knorr method for the glycosylation reactions and the glycosyl hydrogenphosphonate method for phosphorylation. The c

Improved synthesis of 2,3:4,6-di-O-isopropylidene-D-glucopyranose and -D-galactopyranose

2,3:4,6-Di-O-isopropylidene-D-glucopyranose and -D-galactopyranose acetals are conveniently prepared by hydrogenolysis of benzyl 2,3:4,6-di-O-isopropylidene-β-D-glucopyranose and -β-D-galactopyranose in almost quantitative yields in 3 h. This result is in contrast with the sluggish reaction observed (48 h) when the hydrogenolysis was carried out on either anomeric α,β mixtures or on the corresponding α anomers. Copyright (C) 1999 Elsevier Science Ltd.

From sugars to carbocycles. 3. Synthesis of validatol and 4-epi-validatol from mannose and glucose

Validatol (4) and 4-epi-validatol (8) are synthesized from mannose and glucose, respectively. The key step in the synthesis of 4 is the base-induced intramolecular displacement reaction of the epoxy dithiane 14 to yield the six-membered carbocycle 15 excl

Synthesis and biological activities of (4,6-di-O-phosphonato-β-D-mannopyranosyl)methylphosphonate as an analogue of 1L-myo-inositol 1,4,5-trisphosphate

The synthesis of the α and β anomers of the title compound (1) was accomplished from D-mannose.In the key step, the phosphonate analogues of the mannopyranosyl phosphates were prepared by a direct Wadsworth-Emmons condensation of a protected mannose derivative (8) with tetraethyl methylenebisphosphonate under two-phase conditions.In vitro bioassays have shown that the β-anomer (1a) is a potent inhibitor of Ins(1,4,5)P3 3- kinase and inhibits other enzymes.