117285-75-3Relevant academic research and scientific papers
Syntheses of 6-acylcoumarins via highly regioselective fries rearrangements. Total syntheses of the linear acylated coumarins geijerin and dehydrogeijerin
Cairns, Nicholas,Harwood, Laurence M.,Astles, David P.
, p. 7581 - 7590 (2007/10/02)
Methyl 3-(2-acyloxy-4-methoxyphenyl)propanoates (7), prepared in high yield from 7-methoxycoumarin are key intermediates in general and efficient syntheses of 6-acylcoumarins. Under standard Fries rearrangement conditions (7) undergo highly regioselective
EFFICIENT, HIGHLY REGIOSELECTIVE FRIES REARRANGEMENTS OF METHYL 3-(2-ACYLOXY-4-METHOXYPHENYL)PROPANOATES: THE FIRST TOTAL SYNTHESIS OF THE LINEAR ACYLATED COUMARINS GEIJERIN AND DEHYDROGEIJERIN.
Cairns, Nicholas,Harwood, Laurence M.,Astles, David P.
, p. 1311 - 1314 (2007/10/02)
Aluminium chloride catalysed para-Fries rearrangement of methyl 3-(2-acyloxy-4-methoxyphenyl)propanoates (5) in nitromethane furnishes the corresponding 5-acylated products (6) cleanly and in high yield.The rearrangement products may be converted into 6-a
