117290-14-9Relevant academic research and scientific papers
Synthesis of unnatural amino acids from serine derivatives by β-fragmentation of primary alkoxyl radicals
Boto, Alicia,Gallardo, Juan A.,Hernandez, Dacil,Hernandez, Rosendo
, p. 7260 - 7269 (2008/02/11)
(Chemical Equation Presented) The fragmentation of primary alkoxyl radicals has been scarcely used in synthesis since other competing processes (such as oxidation or hydrogen abstraction) usually predominate. However, when serine derivatives were used as
Methods for the synthesis of two or more dicarba bridges in organic compounds
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, (2008/06/13)
Described herein are methods for forming two or more dicarba bridges, as well as new compounds containing dicarba bridges.
One-pot synthesis of aryl glycines and other unnatural amino acids from serine derivatives
Boto, Alicia,Hernández, Rosendo,Montoya, Adriana,Suárez, Ernesto
, p. 8269 - 8272 (2007/10/03)
A mild and highly efficient one-pot synthesis of aryl glycines from easily available serine derivatives is described. This methodology is also applied to the synthesis of other uncommon amino acids.
Reactions of α-substituted glycine derivatives with stannanes
Easton,Peters
, p. 5581 - 5584 (2007/10/02)
α-Benzoyloxy- and α-methoxy-substituted glycine derivatives are more stable than the corresponding bromides, yet they undergo analogous reactions with stannanes. Their reactions with mixtures of hexabutylditin and dialkyl disulphides give α-alkylthio-subs
Reactions of a Glycidyl Radical Equivalent with 2-Functionalised Allyl Stannates
Baldwin, Jack S.,Adlington, Robert M.,Lowe, Christopher,O'Neil, Ian A.,Sanders, Gillian L.,et al.
, p. 1030 - 1031 (2007/10/02)
Reaction of 2-bromo-N-benzoylglycine methyl ester with 2-functionalised allyl stannane reagents under radical conditions provides a new route to α-alkylated amino acids in good yield, as exemplified by the facile synthesis of 4-methylene glutamate.
