1173178-65-8

Basic information

• Product Name: 4-{5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl}benzonitrile
• Synonyms: 4-{5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl}benzonitrile
• CAS NO: 1173178-65-8
• Molecular Weight: 281.701
• Mol File: 1173178-65-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-{5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl}benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl}benzonitrile(1173178-65-8)
• EPA Substance Registry System: 4-{5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl}benzonitrile(1173178-65-8)

Safety Data

• Hazardous Substances Data: 1173178-65-8(Hazardous Substances Data)

Upstream product

• 68496-88-8 ethyl 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-carboxylate 
• 536-40-3 4-chlorobenzoic acid hydrazide 
• 23289-10-3 2-(4-chlorophenyl)-1,3,4-oxadiazole 
• 3058-39-7 4-iodobenzonitrile 

Relevant articles and documents

From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II)

The sphingosine kinase (SK) inhibitor, SKI-II, has been employed extensively in biological investigations of the role of SK1 and SK2 in disease and has demonstrated impressive anticancer activity in vitro and in vivo. However, interpretations of results u

Copper-mediated direct arylation of 1,3,4-oxadiazoles and 1,2,4-triazoles with aryl iodides

The copper-mediated direct arylation of 1,3,4-oxadiazoles and 1,2,4-triazoles with aryl iodides proceeds efficiently in the presence of suitable ligands and bases. This method allows the installation of a variety of aryl moieties bearing a functional group such as ketone, ester, or nitrile so as to enable the facile construction of various functionalized oxadiazole and triazole core π systems.