117324-05-7

Basic information

• Product Name: ETHYL 2-AMINO-4-FLUOROBENZOATE
• Synonyms: ETHYL 2-AMINO-4-FLUOROBENZOATE
• CAS NO: 117324-05-7
• Molecular Formula: C₉H₁₀FNO₂
• Molecular Weight: 183.18
• Product Categories: Esters;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 117324-05-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 271.243 °C at 760 mmHg
• Flash Point: 117.844 °C
• Appearance: /
• Density: 1.219 g/cm³
• Vapor Pressure: 0.007mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.46±0.10(Predicted)
• CAS DataBase Reference: ETHYL 2-AMINO-4-FLUOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-AMINO-4-FLUOROBENZOATE(117324-05-7)
• EPA Substance Registry System: ETHYL 2-AMINO-4-FLUOROBENZOATE(117324-05-7)

Safety Data

• Hazardous Substances Data: 117324-05-7(Hazardous Substances Data)

Usage

General Description

ETHYL 2-AMINO-4-FLUOROBENZOATE, also known as ethyl 2-amino-4-fluorobenzoate, is a chemical compound with the molecular formula C9H10FNO2. It is a white to off-white solid that is mainly used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. ETHYL 2-AMINO-4-FLUOROBENZOATE is known for its potential as an anti-inflammatory and analgesic agent, and its structure includes an amino group and a fluorine atom. It is important to handle ethyl 2-amino-4-fluorobenzoate with care, as it may cause skin and eye irritation and is harmful if ingested or inhaled.

InChI:InChI=1/C9H10FNO2/c1-2-13-9(12)7-4-3-6(10)5-8(7)11/h3-5H,2,11H2,1H3

Upstream product

• 394-27-4 2-acetamido-4-fluorobenzoic acid 
• 446-32-2 4-fluoroanthranilic acid 
• 64-17-5 ethanol 

Downstream Products

• 1038343-02-0 C₁₇H₁₆FNO₃ 
• 1038343-01-9 C₁₆H₁₃ClFNO₃ 
• 16499-57-3 7-fluoro-3H-quinazolin-4-one 
• 196194-86-2 7-(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one 
• 199327-54-3 4-chloro-7-(2-methoxyethoxy)quinazoline 
• 1009368-27-7 2-(2-amino-4-fluorophenyl)propan-2-ol 
• 473416-60-3 2-acetylamino-4-fluorobenzoic acid ethyl ester 

Relevant articles and documents

PLATELET ADP RECEPTOR INHIBITORS

no abstract published

Platelet ADP receptor inhibitors

Novel compounds of formulae (I) to (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof.

Platelet ADP receptor inhibitors

Novel compounds of formulae (I) to (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof.