1173276-76-0Relevant academic research and scientific papers
Cyclization reactions through DDQ-mediated vinyl oxazolidinone oxidation
Liu, Lei,Floreancig, Paul E.
, p. 3152 - 3155 (2009)
Vinyl oxazolidinones react with DDQ to form α,β-unsaturated acyliminium ions in a new method for forming electrophiles under oxidative conditions. Appended nucleophiles undergo 1,4-addition reactions with these intermediates to form cyclic vinyl oxazolidinones with good levels of diastereocontrol, highlighting a new approach to utilizing oxidative carbon-hydrogen bond functionalization to increase molecular complexity.
2,3-dichloro-5,6-dicyano-1,4-benzoquinone-catalyzed teactions employing MnO2 as a stoichiometric oxidant
Liu, Lei,Floreancig, Paul E.
supporting information; experimental part, p. 4686 - 4689 (2010/12/24)
Several oxidative reactions can be effected with MnO2 in the presence of substoichiometric quantities of DDQ. These transformations include oxidative cyclization, deprotection, and dehydrogenation reactions. The use of MnO2 as a terminal oxidant for DDQ-mediated reactions is attractive based on economical and environmental factors.
