1173565-56-4 Usage
Uses
Used in Pharmaceutical Industry:
(3S,4R)-4-(3-fluorophenyl)-4-hydroxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylic acid is used as a potential therapeutic agent for various medical conditions due to its unique structure and potential pharmaceutical properties.
Used in Medicinal Research:
In the field of medicinal research, (3S,4R)-4-(3-fluorophenyl)-4-hydroxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylic acid is utilized for exploring its anti-inflammatory, analgesic, or antibacterial activities, with the aim of developing new drugs for treating various diseases and conditions.
Used in Drug Synthesis:
(3S,4R)-4-(3-fluorophenyl)-4-hydroxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylic acid serves as a key intermediate in the synthesis of more complex pharmaceutical compounds, contributing to the development of novel drugs with improved efficacy and safety profiles.
Used in Drug Delivery Systems:
(3S,4R)-4-(3-fluorophenyl)-4-hydroxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylic acid may also be employed in the development of innovative drug delivery systems, potentially enhancing its bioavailability, targeting specific tissues or cells, and improving the overall therapeutic outcomes of treatments involving this molecule.
Check Digit Verification of cas no
The CAS Registry Mumber 1173565-56-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,3,5,6 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1173565-56:
(9*1)+(8*1)+(7*7)+(6*3)+(5*5)+(4*6)+(3*5)+(2*5)+(1*6)=164
164 % 10 = 4
So 1173565-56-4 is a valid CAS Registry Number.
1173565-56-4Relevant academic research and scientific papers
Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents
Li, Ben,Jones, Eric Dale,Zhou, Enkun,Chen, Li,Baylis, Dean Cameron,Yu, Shanghai,Wang, Miao,He, Xing,Coates, Jonathan Alan Victor,Rhodes, David Ian,Pei, Gang,Deadman, John Joseph,Xie, Xin,Ma, Dawei
scheme or table, p. 5334 - 5336 (2010/10/03)
Modification of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists revealed that introducing a fluoro group at the 3-position of the 3-phenyl group to reduce metabolism did not adversely affect the high potency against HIV infection, and that replacing the piperidine ring with a tropane ring could deliver the most potent anti-HIV agents. Stereochemistry of the substituted tropane ring is essential for maintaining the potent anti-HIV activity because only exo-isomers displayed subnanomolar whole cell activity.
PYROLLIDINE-BASED COMPOUNDS
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Page/Page column 51, (2009/09/05)
A compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof, which can inhibit HIV replication.
PYROLLIDINE-BASED COMPOUNDS
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Page/Page column 50-51, (2009/08/16)
The present invention discloses the compounds of formula ( I ) or a pharmaceutically acceptable derivative, salt or prodrug thereof, which can inhibit HIV replication.
