117358-58-4

Upstream product

• 90-15-3 α-naphthol 
• 89-98-5 2-chloro-benzaldehyde 
• 126-81-8 dimedone 
• 113250-73-0 (2-chloro-benzylidene)-[1]naphthyl-amine 

Downstream Products

• 932748-09-9 C₂₅H₂₂ClNS 
• 117358-67-5 7-(o-chlorophenyl)-10,10-dimethyl-8,9,10,11-tetrahydrobenz[c]acridin-8-one 

Relevant academic research and scientific papers

TiO2 nanoparticles as an efficient catalyst for the one-pot preparation of Tetrahydrobenzo[c]acridines in aqueous media

A series of tetrahydrobenzo[c]acridinone derivatives have been prepared by a one-pot fourcomponent reaction of 1-naphthol, aromatic aldehydes, dimedone, and ammonium acetate in aqueous media using a catalytic amount of titanium dioxide nanoparticles (TiO2 NPs). The advantages of this novel protocol include the excellent yields, operational simplicity, short reaction time, easy work-up, reusability of the catalyst and an environmentally friendly procedure.

A simple and clean procedure for the synthesis of polyhydroacridine and quinoline derivatives: Reaction of Schiff base with 1,3-dicarbonyl compounds in aqueous medium

A clean and simple synthesis of benzo[c]acridine, benzo[a]acridine, pyrido[2,3-c]acridine and benzo[f]quinoline derivatives was accomplished in good to excellent yields via the reaction of Schiff base with 1,3-dicarbonyl compounds in aqueous medium catalyzed by TEBA. The structures were characterized by 1H NMR, IR and elemental analysis, and confirmed by X-ray diffraction study.