113250-73-0

Basic information

• Product Name: 1-Naphthalenamine, N-[(2-chlorophenyl)methylene]-
• CAS NO: 113250-73-0
• Molecular Formula: C17H12ClN
• Molecular Weight: 265.742
• Mol File: 113250-73-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Naphthalenamine, N-[(2-chlorophenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenamine, N-[(2-chlorophenyl)methylene]-(113250-73-0)
• EPA Substance Registry System: 1-Naphthalenamine, N-[(2-chlorophenyl)methylene]-(113250-73-0)

Safety Data

• Hazardous Substances Data: 113250-73-0(Hazardous Substances Data)

Usage

General Description

1-Naphthalenamine, N-[(2-chlorophenyl)methylene]-, also known as 2-((2-chlorophenyl)imino)naphthalen-1-amine, is a chemical compound with the molecular formula C17H12ClN. It is a yellowish solid with a melting point of 134-136 degrees Celsius. 1-Naphthalenamine, N-[(2-chlorophenyl)methylene]- is often used as an intermediate in the synthesis of other organic compounds and can also be used as a pharmaceutical intermediate. It is important to handle this compound with care as it may be harmful if ingested or inhaled and can cause irritation to the skin and eyes.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 134-32-7 1-amino-naphthalene 

Downstream Products

• 1310480-62-6 1-(2-chlorobenzyl)-3,3-dimethyl-1-(naphthalen-1-yl)urea 
• 113250-80-9 (2-chlorobenzyl)(naphthalen-1-yl)amine 
• 117358-58-4 10,10-dimethyl-7-(o-chlorophenyl)-7,10,11,12-tetrahydrobenzo[c]acridin-8(9H)-one 
• 218-38-2 benzo[c]phenanthridine 

Relevant articles and documents

Introduction of (2-CF3)phenyl group via nickel-catalyzed C-CL bond activation and arylation

A simple and mild catalytic arylation via C-Cl bond activation is described. The phenyl group containing a 2-trifluoromethyl group was introduced into the aromatic imine molecules through C,C-coupling reaction between chloroarenes and the organozinc reage

Benzyne Cyclization Route to Benzophenanthridine Alkaloids. Synthesis of Chelerythrine, Decarine, and Nitidine

The alkaloids chelerythrine (8b) and decarine (7c) have been synthesized through a benzyne-mediated cyclization of N-(2-halobenzyl)-1-naphthylamines 4 with KNH2 in ammonia/ether.The 7-hydroxybenzophenanthridine structure 16a proposed for the alkaloid fagaridine is questioned on the basis of comparison with a model compound (16b) synthesized by benzyne cyclization.For the 8,9-oxygenated alkaloids like nitidine (8i), this cyclization proceeded poorly, but a dramatic improvement occurred when LDA/THF at -78 deg C was used instead of KNH2/NH3.