1173706-99-4

Upstream product

• 455-24-3 4-trifluoromethylbenzoic acid 
• 615-43-0 2-iodophenylamine 
• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 

Downstream Products

• 134384-31-9 2-(4-trifluoromethylphenyl)benzothiazole 
• 1321594-90-4 N-[2-(phenylethynyl)phenyl]-4-(trifluoromethyl)benzamide 
• 1415218-83-5 N-{2-[(4-fluorophenyl)ethynyl]phenyl}-4-(trifluoromethyl)benzamide 
• 1105713-95-8 (9H-carbazol-9-yl)(4-(trifluoromethyl)phenyl)methanone 
• 400073-81-6 C₁₄H₁₁F₃N₂O 
• 347-80-8 N-phenyl 4-trifluoromethylbenzamide 
• 1103883-09-5 C₁₉H₁₇F₃INO₃ 

Relevant academic research and scientific papers

Aniline-Type Hypervalent Iodine(III) for Intramolecular Cyclization via C?H Bond Abstraction of Hydrocarbons Containing N- and O-Nucleophiles

We developed a method for the preparation of (diacetoxyiodo)-2-(N-alkylamido)benzene as an aniline-type hypervalent iodine(III). We also achieved direct cyclizations via C?H bond abstraction, such as the Hofmann-L?ffler-Freytag reaction, a direct amination, and a direct lactonization, using the aniline-type hypervalent iodine(III) to obtain corresponding products in high yields. (Figure presented.).

Synthesis of Aminated Phenanthridinones via Palladium/Norbornene Catalysis

An ortho-amination, ipso-C-H arylation mediated by palladium/norbornene cooperative catalysis is reported. This reaction proceeds through a sequential intermolecular C-N bond formation process followed by intramolecular C-H activation of a tethered arene. The products, aminated phenanthridinones, were generated in moderate to good yields. This method is also applicable to the formation of dibenzazepinones.

One-pot preparation of 2-(alkyl)arylbenzoselenazoles from the corresponding N-(acetyl)benzoyl-2-iodoanilines via a microwave-assisted methodology

We report here the first example of a one-pot synthesis of 2-(alkyl)arylbenzoselenazoles from N-(acetyl)benzoyl-2-iodoanilines. The reaction was carried out in the presence of Woollins' reagent under microwave irradiation and resulted in moderate to good yields.

Iodine-catalyzed, stereo- and regioselective synthesis of 4-arylidine-4H-benzo[d][1,3]oxazines and their applications for the synthesis of quinazoline 3-oxides

4-Benzylidene-2-aryl-4H-benzo[d][1,3] oxazines have been synthesized with high stereoselectivity and regioselectivities from 2-alkynylbenzamides in the presence of a catalytic amount of I2. In the reaction mechanism, iodine plays a key role in