117375-00-5

Upstream product

• 39167-47-0 1,1'-bis-(4-chloro-phenyl)-2,2'-selanediyl-bis-ethanone 
• 99-91-2 para-chloroacetophenone 
• 40338-30-5 dichloro-bis-(4-chloro-phenacyl)-λ⁴-selane 

Downstream Products

• 117375-03-8 3,4-Bis-(4-chloro-phenyl)-selenophene 

Relevant academic research and scientific papers

A NOVEL SYNTHESIS OF SELENOPHENES

Reduction of α,α'-diketo selenides with a low-valent titanium reagent usually affords 3,4-dihydroxyselenolanes, from wich the corresponding selenophenes are obtained by acid-catalyzed dehydration.A surprising exception is the formation of 2,4-dihydroy-2,4-di-t-butylselenolane from bis(2-t-butyl-2-oxoethyl) selenide, the former being converted to 2,4-di-t-butylselenophene by acid treatment.

SYNTHESES WITH DIKETO SELENIDES

We report a) a modified synthesis of diketo selenides, b) preparation of 2,5-diacylselenophenes by condensation of diketoselenides with glyoxal, c) preparation of poly-substituted selenophenes by intramolecular reductive coupling reaction of diketo selenides with low-valent titanium reagent under controlled conditions (0 degC) followed by dehydratation of the resulting 3,4-dihydroxyselenolanes, and d) formation of 2,5-dihydroselenophenes and 1,3-dienes by treatment of diketo selenides with the low-valent titanium reagent in refluxing tetrahydrofuran.