1173825-66-5Relevant articles and documents
Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers
Kemnitzer, William,Sirisoma, Nilantha,May, Chris,Tseng, Ben,Drewe, John,Cai, Sui Xiong
scheme or table, p. 3536 - 3540 (2010/03/31)
We report the discovery of N-((benzo[d][1,3]dioxol-5-yl)methyl)-6-phenylthieno[3,2-d]pyrimidin-4-amine (2a) as an apoptosis inducer using our proprietary cell- and caspase-based ASAP HTS assay, and SAR study of HTS hit 2a which led to the discovery of 4-a
