1173839-06-9Relevant academic research and scientific papers
Rapid synthesis of the indole-indolone scaffold via [3+2] annulation of arynes by methyl indole-2-carboxylates
Rogness, Donald C.,Larock, Richard C.
, p. 4003 - 4008 (2009)
The reaction of methyl indole-2-carboxylates and arynes affords a very efficient, high yielding synthesis of a novel indole-indolone ring system, which tolerates considerable functionality, is broad in scope, and proceeds under mild reaction conditions.
NOVEL INDICATOR PLATFORM
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Page/Page column 47, (2010/11/18)
A novel indicator platform comprises a plurality of 1 H-lndol-3-yl indicator compounds that are capable of converting to a signalophore compound in response to an external stimulus. In one class of indicator compounds, the resulting signalophores are 2-benzylideneindoline compounds that are formed by an intermolecular Aldol-type process; in a further class of indicator compounds, the resulting signalophores are 10H-indolo[1,2-a]indole compounds that are formed by an intramolecular Aldol-type process. The indicators can be used in a wide array of applications relating, for example, to biological systems or optical data storage.
Synthesis of substituted indoles from 2-azidoacrylates and ortho-silyl aryltriflates
Hong, Deng,Chen, Zhengbo,Lin, Xufeng,Wang, Yanguang
supporting information; experimental part, p. 4608 - 4611 (2010/12/18)
2-Azidoacrylates react with benzynes in the presence of PPh3 and CsF to afford substituted indoles in good yields. The reaction involves the formation of iminophosphorane and benzyne and a subsequent double cyclization/hydrolysis/air-oxidation cascade. This methodology was utilized to synthesize 10H-indolo[1,2-a]indol-10-ones.
Synthesis of polycyclic indolone and pyrroloindolone heterocycles via the annulation of indole- and pyrrole-2-carboxylate esters with arynes
Giacometti, Robert D.,Ramtohul, Yeeman K.
experimental part, p. 2010 - 2016 (2010/04/04)
A mild and general method for the synthesis of a variety of polycyclic indolone and pyrroloindolone heterocycles via the reaction of indole- and pyrrole-2-carboxylate esters with arynes has been developed. Georg Thieme Verlag Stuttgart.
