37129-23-0Relevant academic research and scientific papers
BACTERIAL EFFLUX PUMP INHIBITORS
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Page/Page column 67-69, (2021/12/08)
Disclosed herein are compounds of formula I: (formula I) and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.
Cleavage of C-C Bonds for the Synthesis of C2-Substituted Quinolines and Indoles by Catalyst-Controlled Tandem Annulation of 2-Vinylanilines and Alkynoates
Ni, Jixiang,Jiang, Yong,An, Zhenyu,Yan, Rulong
supporting information, p. 1534 - 1537 (2018/03/23)
The strategy for the synthesis of C2-substituted indoles and quinolines from 2-vinylanilines and alkynoates through C-C bond cleavage is developed. With these general methods, 2-substituted indoles and quinolines can be accessed via tandem Michael addition and cyclization with no requirement of oxidant. This strategy not only provides a method for the synthesis C2-substituted indoles in good yields through the simultaneous cleavage of C=C and C=C bonds under metal-free conditions but also provides a simple method for the generation of the C2-substituted quinolines in moderate yields via Pd-catalyzed C=C bond cleavage.
ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME
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Paragraph 0103-0106, (2016/10/10)
The present invention relates to a novel compound with an excellent light emitting function, and to an organic electroluminescent device having improved properties such as light emitting efficiency, a driving voltage, lifespan or the like, by comprising t
Cobalt(III)-Catalyzed Redox-Neutral Synthesis of Unprotected Indoles Featuring an N-N Bond Cleavage
Lerchen, Andreas,Vásquez-Céspedes, Suhelen,Glorius, Frank
supporting information, p. 3208 - 3211 (2016/03/12)
A redox-neutral cobalt(III)-catalyzed synthetic approach for the direct synthesis of unprotected indoles showcasing an N-N bond cleavage is reported. The herein newly introduced Boc-protected hydrazines establish a beneficial addition to the limited portfolio of oxidizing directing groups for cobalt(III) catalysis. Moreover, the developed catalytic methodology tolerates a good variety of functional groups.
2-Aroylindoles from o-bromochalcones via Cu(i)-catalyzed SNAr with an azide and intramolecular nitrene C-H insertion
Goriya, Yogesh,Ramana, Chepuri V.
supporting information, p. 7790 - 7792 (2014/07/08)
A simple procedure for the synthesis of 2-aroylindole derivatives comprising a one-pot CuI-catalyzed SNAr reaction of o-bromochalcones with sodium azide and subsequent intramolecular cyclization through nitrene C-H insertion has been developed. This protocol is also applicable with the 2′-bromocinnamates giving the indole-2-carboxylates. This journal is the Partner Organisations 2014.
Synthesis of 3-arylindole-2-carboxylates via copper-catalyzed hydroarylation of o-nitrophenyl-substituted alkynoates and subsequent cadogan cyclization
Yamamoto, Yoshihiko,Yamada, Satoshi,Nishiyama, Hisao
, p. 701 - 706 (2011/05/08)
A two-step route to biologically important 3-arylindole-2-carboxylic esters has been successfully established: o-nitrophenyl-substituted alkynoates underwent copper-catalyzed hydroarylation in the presence of commercially available arylboronic acids to afford 3,3-diarylacrylates, which were then converted to indolecarboxylates via a modified Cadogan cyclization using a molybdenum catalyst and triphenylphosphine. Copyright
Synthesis of substituted indoles from 2-azidoacrylates and ortho-silyl aryltriflates
Hong, Deng,Chen, Zhengbo,Lin, Xufeng,Wang, Yanguang
supporting information; experimental part, p. 4608 - 4611 (2010/12/18)
2-Azidoacrylates react with benzynes in the presence of PPh3 and CsF to afford substituted indoles in good yields. The reaction involves the formation of iminophosphorane and benzyne and a subsequent double cyclization/hydrolysis/air-oxidation cascade. This methodology was utilized to synthesize 10H-indolo[1,2-a]indol-10-ones.
Novel method for synthesis of aryl hydrazones from α-diazo esters: scope and limitations of nucleophiles
Yasui, Eiko,Wada, Masao,Takamura, Norio
experimental part, p. 461 - 468 (2009/04/06)
Aryl hydrazones, the precursor of Fischer indole synthesis, were easily obtained by nucleophilic addition of aryllithium reagents to diazo esters. The aryl hydrazones were converted into indoles in good yields by heating with thionyl chloride in alcohol.
Divergent pathways in the reaction of fischer carbenes and palladium
Lopez-Alberca, Maria P.,Mancheno, Maria J.,Fernandez, Israel,Gomez-Gallego, Mar,Sierra, Miguel A.,Torres, Rosario
, p. 1757 - 1759 (2008/02/02)
The Pd-catalyzed reaction of β-arylaminochromium(0) carbene complexes produces by transmetalation the first isolated and X-ray structurally characterized bis-Pd(II) carbene complex, as well as other alternative reaction pathways, such as the oxidative addition-transmetalation sequence, not seen before in this chemistry.
Novel approach to arylhydrazones, the precursor for Fischer indole synthesis, via diazo esters derived from α-amino acid esters
Yasui, Eiko,Wada, Masao,Takamura, Norio
, p. 743 - 746 (2007/10/03)
A novel method for synthesizing arylhydrazones, the precursor for Fischer indole synthesis, using aryllithium reagents and α-diazo esters that are easily obtained from α-amino acid esters, is described.
