1173883-19-6Relevant articles and documents
The design, synthesis and evaluation of hypoxia-activated pro-oligonucleotides
Zhang, Nan,Tan, Chunyan,Cai, Puqin,Zhang, Peizhuo,Zhao, Yufen,Jiang, Yuyang
supporting information; experimental part, p. 3216 - 3218 (2009/12/01)
Hypoxia-activated pro-oligonucleotides were synthesized through the commercial phosphoramidite method, and could be readily cleaved to form normal oligos with good hypoxia selectivity in vitro under the effect of reductases, as well as in tumor cell extra