1173887-63-2

Upstream product

• 1027137-63-8 [(2R,4S,5S)-5-(N-Boc-L-phenylalanylamido)-4-hydroxy-2,7-dimethyloctanoyl] N'-isobutyl amide 
• 99-34-3 3,5-dinitrobenzoic acid 

Relevant academic research and scientific papers

Synthesis and preliminary evaluation of peptidomimetic inhibitors of human β-secretase

Based on the structure of OM99-2 and the X-ray crystal structure of its complex with β-secretase, a series of compounds containing the Leu*Ala hydroxyethylene isostere as a scissile bond substitution were designed. 31 compounds were synthesized and their