1173897-77-2 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-hydroxy-2-methoxyethyl)-1,5-naphthyridin-2(1H)-one is used as a potential therapeutic agent for various applications due to its structural features and biological activity. Its hydroxy and methoxy groups may enhance its interactions with biological targets, making it a promising candidate for further research and development.
Used in Antiviral Applications:
1-(2-hydroxy-2-methoxyethyl)-1,5-naphthyridin-2(1H)-one is used as an antiviral agent, potentially inhibiting viral replication and reducing the severity of viral infections. Its specific mode of action and efficacy against various viruses need to be investigated through further research.
Used in Antibacterial Applications:
1-(2-hydroxy-2-methoxyethyl)-1,5-naphthyridin-2(1H)-one is used as an antibacterial agent, potentially targeting bacterial cell processes and inhibiting their growth. Its effectiveness against different bacterial strains and resistance potential should be explored in future studies.
Used in Anti-inflammatory Applications:
1-(2-hydroxy-2-methoxyethyl)-1,5-naphthyridin-2(1H)-one is used as an anti-inflammatory agent, potentially reducing inflammation and alleviating symptoms associated with various inflammatory conditions. Its specific anti-inflammatory mechanisms and potential side effects require further investigation.
Note: The uses mentioned above are based on the potential of the compound's structural features and the class it belongs to. Actual applications and efficacy will depend on the results of further research and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 1173897-77-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,3,8,9 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1173897-77:
(9*1)+(8*1)+(7*7)+(6*3)+(5*8)+(4*9)+(3*7)+(2*7)+(1*7)=202
202 % 10 = 2
So 1173897-77-2 is a valid CAS Registry Number.
1173897-77-2Relevant academic research and scientific papers
Blanco, Delia,Perez-Herran, Esther,Cacho, Mónica,Ballell, Lluís,Castro, Julia,Del Río, Rubén González,Lavandera, José Luis,Remui?án, Modesto J.,Richards, Cindy,Rullas, Joaquin,Vázquez-Mu?iz, María Jesús,Woldu, Ermias,Zapatero-González, María Cleofé,Angulo-Barturen, I?igo,Mendoza, Alfonso,Barros, David
, p. 1868 - 1875 (2015)
One way to speed up the TB drug discovery process is to search for antitubercular activity among compound series that already possess some of the key properties needed in anti-infective drug discovery, such as whole-cell activity and oral absorption. Here, we present MGIs, a new series of Mycobacterium tuberculosis gyrase inhibitors, which stem from the long-term efforts GSK has dedicated to the discovery and development of novel bacterial topoisomerase inhibitors (NBTIs). The compounds identified were found to be devoid of fluoroquinolone (FQ) cross-resistance and seem to operate through a mechanism similar to that of the previously described NBTI GSK antibacterial drug candidate. The remarkable in vitro and in vivo antitubercular profiles showed by the hits has prompted us to further advance the MGI project to full lead optimization.
NAPHTHYRIDIN-2 (1 H)-ONE COMPOUNDS USEFUL AS ANTIBACTERIALS
-
, (2010/08/08)
Compounds of Formula (I) wherein substituents R1, R2 and R5 are as defined, and Ar represents substituted phenyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiazolyl, furanyl, imidazolyl and thiophenyl substituted by a hydroxyalkyl substituent and an optional other substituent; compositions containing them, their use in therapy, including their use as antibacterials, for example in the treatment of tuberculosis, and methods for the preparation of such compounds, are provided.
