1173978-77-2

Upstream product

• 1173978-62-5 9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-6-carbaldehyde 
• 1173978-60-3 methyl 9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-6-carboxylate 
• 1173983-85-1 methyl 4-chloro-2-[(2,4-dichlorophenyl)amino]-1-(3-hydroxypropyl)-1H-benzimidazole-7-carboxylate 
• 1173983-84-0 methyl 3-amino-4-chloro-2-[(3-hydroxypropyl)amino]benzoate 
• 1173983-71-5 methyl 3-amino-2-[(3-hydroxypropyl)amino]benzoate 
• 1173985-19-7 C₁₉H₁₈Cl₃N₃O₅S 
• 1173978-61-4 [9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-yl]methanol 
• 1173983-70-4 methyl 2-[(3-hydroxypropyl)amino]-3-nitrobenzoate 
• 53553-14-3 2-chloro-3-nitrobenzoic acid methyl ester 
• 3970-35-2 2-chloro-3-nitrobezoic acid 

Downstream Products

• 1173978-81-8 (1Z)-1-[9-Chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-yl]propan-1-one O-ethyloxime 
• 1173978-80-7 (1E)-1-[9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-yl]propan-1-one O-ethyloxime 
• 1173978-79-4 (1Z)-1-[9-Chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-yl]propan-1-one O-methyloxime 
• 1173978-78-3 (1E)-1-[9-chloro-1-(2,4-dichlorophenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazol-6-yl]propan-1-one O-methyloxime 

Relevant academic research and scientific papers

Discovery of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazoles as novel class of corticotropin releasing factor 1 receptor antagonists

A new class of corticotropin releasing factor 1 (CRF1) receptor antagonists characterized by a tricyclic core ring was designed and synthesized. Novel tricyclic derivatives 2a–e were designed as CRF1 receptor antagonists based on con