1174038-65-3 Usage
Uses
Used in Medicinal Chemistry:
1-(Phenylsulfonyl)-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine is used as a building block for the synthesis of biologically active molecules, such as kinase inhibitors and enzyme modulators, due to its unique structure and functional groups.
Used in Drug Development:
In the pharmaceutical industry, 1-(Phenylsulfonyl)-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine is utilized for its potential to contribute to the development of new drugs, particularly in the area of kinase inhibition and enzyme modulation, which are important for treating various diseases.
Used in Synthetic Chemistry:
1-(Phenylsulfonyl)-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine is used as a versatile synthetic intermediate in organic synthesis, particularly for participating in Suzuki-Miyaura cross-coupling reactions, which broadens its applicability in creating a diverse range of chemical compounds.
Further research and exploration of 1-(Phenylsulfonyl)-3-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine's properties and potential applications in drug discovery are necessary to fully harness its capabilities in the fields of medicinal chemistry and pharmaceutical development.
Check Digit Verification of cas no
The CAS Registry Mumber 1174038-65-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,4,0,3 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1174038-65:
(9*1)+(8*1)+(7*7)+(6*4)+(5*0)+(4*3)+(3*8)+(2*6)+(1*5)=143
143 % 10 = 3
So 1174038-65-3 is a valid CAS Registry Number.
1174038-65-3Relevant academic research and scientific papers
Discovery and optimization of a novel series of dyrk1b kinase inhibitors to explore a MEK resistance hypothesis
Kettle, Jason G.,Ballard, Peter,Bardelle, Catherine,Cockerill, Mark,Colclough, Nicola,Critchlow, Susan E.,Debreczeni, Judit,Fairley, Gary,Fillery, Shaun,Graham, Mark A.,Goodwin, Louise,Guichard, Sylvie,Hudson, Kevin,Ward, Richard A.,Whittaker, David
, p. 2834 - 2844 (2015/04/14)
Potent and selective inhibitors of Dyrk1B kinase were developed to explore the hypothesis, based on siRNA studies, that Dyrk1B may be a resistance mechanism in cells undergoing a stress response.
4 (PYRROLO[2,3-C]PYRIDINE-3-YL)PYRIMIDIN-2-AMINE DERIVATIVES
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Page/Page column 13-14, (2010/12/18)
Compounds of the formula (I), in which R1, R2, R3, R4 and R5 have the meanings indicated in Claim 1, are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumours
