67058-76-8

Usage

Uses

3-Bromo-1H-pyrrolo[2,3-c]pyridine is a useful reactant for regioselective halogenation.

InChI:InChI=1/C7H5BrN2/c8-6-3-10-7-4-9-2-1-5(6)7/h1-4,10H

Upstream product

• 271-29-4 6-azaindole 

Downstream Products

• 956003-06-8 3-bromo-1-methyl-1H-pyrrolo[2,3-c]pyridine 
• 1310556-92-3 3-bromo-1-[(4-nitrophenyl)sulfonyl]-1H-pyrrolo[2,3-c]pyridine 
• 1174038-64-2 3-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine 
• 1594092-37-1 N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine 
• 1174038-66-4 3-(2-chloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine 
• 1174038-65-3 1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine 

Relevant academic research and scientific papers

Regioselective halogenation of 6-azaindoles: Efficient synthesis of 3-halo-2,3-disubstituted-6-azaindole derivatives

A mild and efficient synthesis of 3-halo-2-substituted-6-azaindoles was developed by regioselective halogenation of 6-azaindole systems. The transformation was achieved with copper(II) bromide in acetonitrile at room temperature. Georg Thieme Verlag Stutt

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Potent and selective inhibitors of Dyrk1B kinase were developed to explore the hypothesis, based on siRNA studies, that Dyrk1B may be a resistance mechanism in cells undergoing a stress response.

Practical regioselective bromination of azaindoles and diazaindoles

A mild and efficient synthesis of various 3-brominated azaindoles and diazaindoles was developed by regioselective halogenation of the parent systems. This practical and high-yielding transformation was achieved with copper(II) bromide in acetonitrile at

Novel non-nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. 6. 2-Indol-3-yl- and 2-azaindol-3-yl- dipyridodiazepinones

Modification of the non-nucleoside inhibitor of HIV-1 reverse transcriptase nevirapine (Viramune) by incorporation of a 2-indolyl substituent confers activity against several mutant forms of the enzyme.