117411-41-3

Upstream product

• 52200-05-2 4-methanesulfonyloxy-3-methoxybenzaldehyde 
• 117411-40-2 1-chloromethyl-3-methoxy-4-phenylthiobenzene 
• 117411-53-7 1-hydroxymethyl-3-methoxy-4-phenylthiobenzene 
• 122415-03-6 3-Methoxy-4-phenylsulfanyl-benzaldehyde 
• 121-33-5 vanillin 
• 143-33-9 sodium cyanide 

Downstream Products

• 197894-16-9 (4-Benzenesulfinyl-3-methoxy-phenyl)-acetonitrile 
• 197894-17-0 2-(3-Methoxy-4-phenylsulfanyl-phenyl)-3-oxo-propionitrile 
• 117411-21-9 8-(3-methoxy-4-phenylsulfenylphenyl)pyrazolo[1,5-a]-1,3,5-triazine-4(1H)-one 
• 197894-19-2 5-Amino-4-(3-methoxy-4-phenylsulfanyl-phenyl)-pyrazole-1-carboxylic acid amide 
• 197894-18-1 2-(4-Benzenesulfinyl-3-methoxy-phenyl)-3-oxo-propionitrile 

Relevant academic research and scientific papers

Asymmetric synthesis of a xanthine dehydrogenase inhibitor (S)-(-)-BOF-4272 : Mechanism of chiral diaryl sulfoxide formation

A pyrazolotriazine derivative (BOF-4272), a potent xanthine dehydrogenase inhibitor, was synthesized in good yield via 9 steps from vanillin. The asymmetric synthesis was achieved effectively by a modified Oae's asymmetric oxidation of diaryl sulfide. A m

Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor

The invention discloses a pyrimidien derivative expressed in Formula [I]: STR1 where R 1 denotes a hydrogen atom or hydroxyl group, R 2 denotes a hydrogen atom, lower alkoxycarbonyl group, lower alkoxy group, halogen atom, lower alkyl group, cycloalkyl group with 3 to 8 carbon atoms, lower alkoxycarbonyl lower alkyl group, carboxyl group, carboxy lower alkyl group, group: --CONHR 6 (R 6 represents a hydrogen atom, a phenyl group, which may possess halogen atom, or lower alkyl group), cyano group, phenyl group which may possess a group selected from the group consisting of hydroxyl group, halogen atom, lower alkyl group, lower alkoxy group and phenylthio group as a substituent, phenyl lower alkyl group which may possess a group selected from the group consisting of hydroxyl group and lower alkoxy group as a substituent on a phenyl ring, lower alkanoyloxy lower alkyl group, benzoyl group, lower alkanoyl group which may possess a halogen atom, or hydroxy lower alkyl group which may possess a group selected from the group consisting of phenyl group and halogen atom as a substituent, R 3 denotes a hydrogen atom, hydroxyl group, lower alkyl group, cycloalkyl group with 3 to 8 carbon atoms, halogen lower alkyl group, or phenyl group, R 4 denotes a hydrogen atom, lower alkyl group, or lower alkoxy group, and R 5 denotes a hydrogen atom, lower alkyl group, lower alkoxy lower alkyl group, or halogen lower alkyl group; provided that R 2 and R 3 may be bonded to each other to form a lower alkylene group with 3 to 5 carbon atoms, or its pharmaceutically available salt. This derivative is excellent in therapeutic effects of benign prostatic hypertrophy, prostatic carcinoma, female hairiness, male baldness or pimple as an androgen inhibitor.