1174289-21-4

Basic information

• Product Name: (R )-1-Amino-3-methoxy-propan-2-ol
• Synonyms: (R)-1-Amino-3-methoxy-2-propanol;(2R)-1-amino-3-methoxypropan-2-ol;(R )-1-Amino-3-methoxy-propan-2-ol
• CAS NO: 1174289-21-4
• Molecular Formula: C₄H₁₁NO₂
• Molecular Weight: 105.14
• Product Categories: pharmacetical
• Mol File: 1174289-21-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R )-1-Amino-3-methoxy-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (R )-1-Amino-3-methoxy-propan-2-ol(1174289-21-4)
• EPA Substance Registry System: (R )-1-Amino-3-methoxy-propan-2-ol(1174289-21-4)

Safety Data

• Hazardous Substances Data: 1174289-21-4(Hazardous Substances Data)

Usage

General Description

(R)-1-amino-3-methoxypropan-2-ol, also known as (R)-3-Amino-1-methoxypropan-2-ol or (R)-tert-Leucinol, is an organic compound belonging to the class of alcohols. It is a chiral molecule, meaning it has a non-superimposable mirror image, and the prefix "(R)" indicates its stereochemistry. (R)-1-amino-3-methoxypropan-2-ol is commonly used as a chiral auxiliary in organic synthesis, specifically in the formation of chiral amines and amino alcohols. It can also act as a ligand in catalytic asymmetric synthesis. (R)-1-amino-3-methoxypropan-2-ol has applications in the pharmaceutical and agrochemical industries, where its enantiopure form is utilized in the synthesis of bioactive compounds and crop protection agents. Overall, its stereochemical properties and versatile applications make it a valuable building block in organic chemistry.

Upstream product

• 922522-04-1 C₄H₉N₃O₂ 
• 64491-70-9 R(-)-glycidyl methyl ether 

Downstream Products

• 922522-05-2 (R)-3-methoxy-1-(4-monomethoxytrityl)aminopropan-2-ol 

Relevant articles and documents

1-HETEROARYL-INDOLINE-4-CARBOXAMIDES AS MODULATORS OF GPR52 USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO

The present invention relates to compounds of Formula (la) and pharmaceutical compositions thereof that modulate the activity of GPR52. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a GPR52-mediated disorder (e.g., Huntington's disease, schizophrenia, bipolar disorder, attention deficit hyperactivity disorder (ADHD), or Tourette's syndrome); an extrapyramidal or movement disorder; a motor disorder; a hyperkinetic movement disorder; a psychotic disorder; catatonia; a mood disorder; a depressive disorder; an anxiety disorder; obsessive-compulsive disorder (OCD); an autism spectrum disorder; a prolactin-related disorder (e.g., hyperprolactinemia); a neurocognitive disorder; a trauma- or stressor-related disorder (e.g., posttraumatic stress disorder (PTSD)); a disruptive, impulse-control, or conduct disorder; a sleep-wake disorder; a substance-related disorder; an addictive disorder; a behavioral disorder; hypofrontality; an abnormality in the tuberoinfundibular, mesolimbic, mesocortical, or nigrostriatal pathway; decreased activity in the striatum; cortical dysfunction; neurocognitive dysfunction; and conditions related thereto.

Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides

We developed new amino linker reagents for an oligonucleotide (ONT) terminus. These reagents consist of an aminoethyl carbamate main linkage and a side-chain residue, which was a naphthylmethoxymethyl, methoxymethyl, or methyl group or a hydrogen atom. Th