1174334-38-3Relevant academic research and scientific papers
The synthesis of 4-(3,3-dimethyl-3H-pyrrolo[2,3-f] quinolin-2-yl)pyrazoles and 4-(3,3-dimethyl-3H-pyrrolo[3,2-h] quinolin-2-yl)pyrazoles
Rashidi,Afghan,Baradarani, Mehdi M.,Jouleb, John A.
, p. 428 - 431 (2009)
(Chemical Equation Presented) 5-Hydrazinoquinoline and 8-hydrazinoquinoline were converted via Fischer syntheses with 3-methylbutan-2-one into pyrido-indolenines 2,3,3-trimethyl-3H-pyrrolo[2,3-f]quinoline 7 and 2,3,3-trimethyl-3H-pyrrolo[ 3,2-h]quinoline 11, respectively. Exposure of the indolenines to the Vilsmeier reagent produced aminomethylene-malondialdehydes 8 and 12, which reacted with hydrazine or arylhydrazines to give 4-(3H-pyrrolo[2,3-f]quinolin-2-yl)- and 4-(3H-pyrrolo[3,2-h]quinolin-2-yl)- pyrazoles, 9 and 13.
