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Relevant academic research and scientific papers

Pectin; hetero polysaccharide as a green and natural catalyst for the synthesis of dihydro-2-oxopyrroles and 3,4,5-trisubstituted furan-2(5H)-ones

Use of green and biodegradable catalyst in organic synthesis is undeniable. Easy access, inexpensive, natural and green catalysts are valuable. In this study, a green procedure by using pectin as a green and natural catalyst for the one-pot synthesis of dihydro-2-oxopyrroles and 3,4,5-trisubstituted furan-2(5H)-ones at ambient temperature in aqueous media has been developed. This methodology has some advantages such as: use of a hetero polysaccharide as a easy access and biodegradable catalyst, clean work-up and no need to column chromatography.

Vitamin B12: An efficient type catalyst for the one-pot synthesis of 3,4,5-trisubstituted furan-2(5H)-ones and N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates

Vitamin B12 was applied as catalyst for the one-pot three-component synthesis of 3,4,5-trisubstituted furan-2(5H)-ones from the condensation between aldehydes, amines and dialkylacetylendicarboxylates at ambient temperature in EtOH. In addition, N-aryl-3-aminodihydropyrrol-2-one-4-carboxylates were synthesised using mentioned catalyst at ambient temperature in EtOH from condensation between formaldehyde, amines, and dialkylacetylenedicarboxylates. This methodology has number of advantages such as: use of green and nonhazardous catalyst, clean work up, short reaction times, high yields and no need to column chromatography.

Facile and efficient synthesis of 3,4,5-substituted furan-2(5H)-ones by using β-cyclodextrin as reusable catalyst

3,4,5-Substituted furan-2(5H)-one derivatives were synthesized by using β-cyclodextrin as a catalyst in water via biomimetic approach. β-Cyclodextrin can be recovered and reused.