1174498-41-9Relevant academic research and scientific papers
Rapid Access to Kinase Inhibitor Pharmacophores by Regioselective C-H Arylation of Thieno[2,3-d]pyrimidine
Flesch, Kaylin Nicole,Itami, Kenichiro,Murakami, Kei,Yamada, Shuya
supporting information, p. 1547 - 1551 (2020/03/13)
Regioselective C-H arylations of thieno[2,3-d]pyrimidine are accomplished under palladium catalysis. Thieno[2,3-d]pyrimidines react with aryl iodides at the C6-position and with aryl boronic acids at the C5-position, showing excellent regioselectivity. Me
Iridium complex containing thieno-[2,3-d] pyrimidine group and application in electroluminescence device
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, (2018/03/09)
The invention disclose an iridium complex containing a thieno-[2,3-d] pyrimidine group and application of the iridium complex as a phosphorescence object material in an electroluminescence device. Main ligands in the series of iridium complex molecules are derivatives containing thieno-[2,3-d] pyrimidine heterocyclic rings. Auxiliary ligands are diacetone, tetramethyl-3,5-heptanedione or 2-pyridine carboxylic acid. The iridium complex has the characteristics of high luminous efficiency, stable chemical property, easy purification and the like, and the application of the iridium complex as thephosphorescence object material in an electroluminescence device has excellent luminous efficiency, electron mobility and stability. Through the modification of the main ligands, the luminous wavelength and efficiency of the complex can be adjusted in a visible light band.
Unexpected C - O bond formation in Suzuki coupling of 4-chlorothieno[2,3-d] pyrimidines
Perspicace, Enrico,Hesse, Stephanie,Kirsch, Gilbert,Yemloul, Mehdi,Lecomte, Claude
experimental part, p. 459 - 464 (2009/09/28)
(Chemical Equation Presented) Palladium-catalyzed Suzuki reactions were performed on 4-chlorothieno[2,3-d]pyrimidines under classical heating conditions and under microwave irradiation. Some unexpected results were obtained during this study as two kinds of compounds were isolated depending on the conditions used. A careful investigation of experimental details has shown that the expected CAC bond formation occurred when degassed solvents were used (both in classical and microwave heating) whereas an unexpected CAO bond formation happened when solvents were not degassed with argon-bubbling before use.
