117452-73-0

Upstream product

• 104006-65-7 1,5-anhydro-3-O-benzoyl-2,6-dideoxy-L-arabino-hex-1-enitol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 98-88-4 benzoyl chloride 
• 53657-42-4 L-rhamnal 

Downstream Products

• 1607437-71-7 3-O-benzoyl-4-O-tert-butyldimethylsilyl-2,6-dideoxy-L-hexopyranoside acetate 
• 1607437-72-8 3-O-benzoyl-4-O-tert-butyldimethylsilyl-2,6-dideoxy-L-hexopyranoside acetate 
• 117475-68-0 ((2S,3S,4S,6S)-6-{(2S,3S,4S,6S)-6-[(1S,2R)-1-((S)-1-Benzyloxy-ethyl)-3-(diphenyl-phosphinoyl)-2-methyl-propoxy]-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy}-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy)-tert-butyl-dimethyl-silane 
• 117452-75-2 (2S,3S,4S,6S)-6-[(1S,2R)-1-((S)-1-Benzyloxy-ethyl)-3-(diphenyl-phosphinoyl)-2-methyl-propoxy]-4-methoxy-2-methyl-tetrahydro-pyran-3-ol 

Relevant academic research and scientific papers

Scope and limitations of 2-deoxy- and 2,6-dideoxyglycosyl bromides as donors for the synthesis of β-2-deoxy- and β-2,6-dideoxyglycosides

It is shown that 2-deoxy- and 2,6-dideoxyglycosyl bromides can be prepared in high yield (72-94%) and engaged in glycosylation reactions with β:α selectivities ≥6:1. Yields of product are 44-90%. Fully armed 2-deoxyglycoside donors are viable, while 2,6-d

APPROACHES TO AVERMECTIN ASSEMBLY: ELABORATION OF AN α-L-OLEANDROSYL-α-L-OLEANDROSIDE DERIVATIVE

A stereospecific synthesis of the disaccharide moiety of avermectin A2b has been accomplished in 11 steps from commercially available 3-pentyn-2-ol and L-rhamnal.