117461-47-9Relevant academic research and scientific papers
Regioselective dehydroxytrifluoromethylthiolation of allylic and propargylic alcohols with AgSCF3
Liu, Yin-Li,Xu, Xiu-Hua,Qing, Feng-Ling
supporting information, p. 953 - 956 (2019/03/07)
The reaction of easily available Morita–Baylis–Hillman (MBH) alcohols with AgSCF3 in the presence of n-Bu4NI and KI affords primary allylic SCF3 products in high yields and excellent regioselectivities. This regioselective dehydroxytrifluoromethylthiolation protocol could also be extended to propargylic alcohols for the preparation of the primary propargylic SCF3 products.
Synthesis of Chiral α-Trifluoromethylamines with 2,2,2-Trifluoroethylamine as a "building Block"
Li, Xiaoyuan,Su, Jinhuan,Liu, Zhourujun,Zhu, Yuanyuan,Dong, Zhenghao,Qiu, Shuai,Wang, Jiayi,Lin, Li,Shen, Zhiqiang,Yan, Wenjin,Wang, Kairong,Wang, Rui
supporting information, p. 956 - 959 (2016/03/15)
The β-isocupreidine, a cinchonine derived alkaloid, catalyzed asymmetric SN2′-SN2′ reaction between N-2,2,2-trifluoroethylisatin ketimines and MBH type carbonates was realized in a simple and efficient way. A series of chiral α-trifl
Catalytic Asymmetric Synthesis of α-Methylene-β-hydroxy-ketones
Barrett, Anthony G. M.,Kamimura, Akio
, p. 1755 - 1756 (2007/10/02)
Condensation of an α,β-unsaturated ketone, an aldehyde and trimethylsilyl phenyl sulfide or selenide, catalysed by a chiral (acyloxy)borane, and subsequent oxidative elimination gives the title adducts in high enantiomeric excess.
A General Synthesis of α-Methylene-β-Hydroxyalkanones
Basavaiah, D.,Bharathi, T. K.,Gowriswari, V. V. L.
, p. 1893 - 1896 (2007/10/02)
Several α-methylene-β-hydroxyalkanones have been prepared by 1,4-diazabicyclooctane (DABCO) catalyzed coupling of α,β-unsaturated ketones with aldehydes.
