117471-65-5Relevant academic research and scientific papers
Synthesis of Bridged Diketopiperazines by Using the Persistent Radical Effect and a Formal Synthesis of Bicyclomycin
Amatov, Tynchtyk,Pohl, Radek,Císa?ová, Ivana,Jahn, Ullrich
supporting information, p. 12153 - 12157 (2015/10/12)
A conceptually new and unified approach to diverse bridged diketopiperazines (DKPs) with widely variable ring sizes was developed by taking advantage of the persistent radical effect. This method enables synthesis of the core structures of bridged DKP alk
Versatile New Approach to the Synthesis of Monosubstituted and Bicyclic Piperazine-2,5-diones: Unusual in Situ Generation and Enolate Addition to a Cumulene
Williams, Robert M.,Kwast, Andrzej
, p. 5785 - 5787 (2007/10/02)
Dichloroacetyl chloride condenses with glycinamide 9 to furnish the versatile precursor 10, which cyclizes to the mono (ether) substituted piperazinediones 11 upon treatment with alkoxides.A new intramolecular enolate C-C bond-forming cyclization from the
