1174715-97-9Relevant academic research and scientific papers
Asymmetric synthesis of (+)-tanikolide and the β-methyl-substituted analogues of (+)-tanikolide and (-)-malyngolide
Doran, Robert,Duggan, Lesley,Singh, Surrendra,Duffy, Colm D.,Guiry, Patrick J.
, p. 7097 - 7106 (2012/01/03)
The δ-lactone-containing natural product (+)-tanikolide, a brine shrimp toxin and antifungal compound, was synthesized in nine steps with an overall yield of 26.4 % by employing Sharpless asymmetric epoxidation and ZrCl4-catalyzed intramolecula
Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula
Gutierrez, Marcelino,Andrianasolo, Eric H.,Shin, Won Kyo,Goeger, Douglas E.,Yokochi, Alexandre,Schemies, Joerg,Jung, Manfred,France, Dennis,Cornell-Kennon, Susan,Lee, Eun,Gerwick, William H.
experimental part, p. 5267 - 5275 (2009/12/08)
(Chemical Equation Presented) Tanikolide seco-acid 2 and tanikolide dimer 3, the latter a novel and selective SIRT2 inhibitor, were isolated from the Madagascar marine cyanobacterium Lyngbya majuscula. The structure of 2, isolated as the pure R enantiomer
