1174738-57-8

Basic information

• Product Name: 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylic acid
• Synonyms: 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylic acid
• CAS NO: 1174738-57-8
• Molecular Weight: 313.3
• Mol File: 1174738-57-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylic acid(1174738-57-8)
• EPA Substance Registry System: 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylic acid(1174738-57-8)

Safety Data

• Hazardous Substances Data: 1174738-57-8(Hazardous Substances Data)

Upstream product

• 98-98-6 2-Picolinic acid 
• 1174738-63-6 C₁₄H₉F₃N₂S 
• 5470-22-4 4-chloropicolinic acid 
• 25697-55-6 m-trifluoromethylbenzyl mercaptan 

Downstream Products

• 1174738-77-2 ethyl 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxylate 
• 1373441-81-6 4-(3-trifluoromethylbenzylsulfanyl)pyridine-2-carboxamide 

Relevant articles and documents

The synthesis and antimycobacterial properties of 4-(substituted benzylsulfanyl)pyridine-2-carboxamides

4-(Substituted benzylsulfanyl)pyridine-2-carboxamides 6 were synthesized by a three-step synthesis starting from 4-chloropyridine-2-carboxylic acid and substituted benzyl thiols, with the exception of nitroderivatives. The compounds were evaluated for their anti-TB activity against M. tuberculosis, non-tuberculous mycobacteria (M. kansasii and M. avium), and MDR strains of M. tuberculosis. The activities expressed as the minimum inhibitory concentration (MIC) fall into the range of 8-250 μmol/L. The substances exhibited similar activities against both sensitive and resistant strains. ARKAT-USA, Inc.