1174751-09-7Relevant academic research and scientific papers
Asymmetric construction of quaternary α-nitro amides by palladium-catalyzed C(sp3)-H arylation
Kong, Wei-Xin,Xie, Shi-Jing,Cao, Chen-Yao-Zi,Zhang, Chao-Wei,Wang, Chuanyong,Duan, Wei-Liang
supporting information, p. 2292 - 2295 (2020/03/04)
Pd-Catalyzed enantioselective C(sp3)-H arylation of N-(o-Br-aryl) anilides has been disclosed, and quaternary α-nitro amides were constructed with up to 98% ee. The presence of the nitro group on the substrate enables the progress of the reaction and the ready transformation of the product to optically active quaternary amino acid derivatives.
Telescoped enolate arylation/HWE procedure for the preparation of 3-alkenyl-oxindoles: The first synthesis of soulieotine
Millemaggi, Alessia,Perry, Alexis,Whitwood, Adrian C.,Taylor, Richard J. K.
scheme or table, p. 2947 - 2952 (2009/10/11)
A. telescoped sequence involving palladium-catalysed intramolecular enolate arylation followed by an in situ HWE olefination has been developed to provide rapid access to 3-alkenyl-oxindoles. This "one-pot" process, which is greatly accelerated by microwa
