1175-88-8

Basic information

• Product Name: 10-[3-(dimethylammonio)-2-methylpropyl]-10H-phenothiazinium [R-(R*,R*)]-tartrate
• Synonyms: 10-[3-(dimethylammonio)-2-methylpropyl]-10H-phenothiazinium [R-(R*,R*)]-tartrate
• CAS NO: 1175-88-8
• Molecular Formula: C₄H₆O₆*2C₁₈H₂₂N₂S*2H
• Molecular Weight: 448.53252
• EINECS: 214-642-6
• Mol File: 1175-88-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 420.3°Cat760mmHg
• Flash Point: 208°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 2.84E-07mmHg at 25°C
• CAS DataBase Reference: 10-[3-(dimethylammonio)-2-methylpropyl]-10H-phenothiazinium [R-(R*,R*)]-tartrate(CAS DataBase Reference)
• NIST Chemistry Reference: 10-[3-(dimethylammonio)-2-methylpropyl]-10H-phenothiazinium [R-(R*,R*)]-tartrate(1175-88-8)
• EPA Substance Registry System: 10-[3-(dimethylammonio)-2-methylpropyl]-10H-phenothiazinium [R-(R*,R*)]-tartrate(1175-88-8)

Safety Data

• Hazardous Substances Data: 1175-88-8(Hazardous Substances Data)

Usage

Chemical Family

Phenothiazine

Common Use

Reagent in biological and biochemical research

Type of Compound

Cationic dye

Affinity

High affinity for nucleic acids

Application

Staining DNA and RNA in agarose gel electrophoresis

Salt Form

Tartrate salt form

Stabilization

Helps to stabilize the molecule

Solubility

More soluble in water due to tartrate salt form

Laboratory Handling

Easy handling and usage

Value

Valuable tool in molecular biology

Purpose

Visualization and analysis of nucleic acids in various laboratory applications

InChI:InChI=1/C18H22N2S.C4H6O6/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;5-1(3(7)8)2(6)4(9)10/h4-11,14H,12-13H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

Upstream product

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Relevant articles and documents

Reactions of thiyl radicals with phenothiazines and other antioxidants in aqueous solutions. A pulse radiolysis study.

Reaction rate constants of thiyl radicals with phenothiazines, promethazine (PMZ), chlorpromazine (CPZ), prochlorperazine (PPZ), trimeperazine tarterate (TPZ), and other antioxidants, e. g., ascorbic acid and 2,2-azinobis(3-ethyl benzthiazoline-6 sulphonate) (ABTS) have been estimated using pulse radiolysis technique.In general they are quite high (108-109 M-1 s-1).The k value of cysteine, cysteamine, mercaptoethanol, and mercaptopropionic acid with similar structures and molecular weights are more or less similar for PMZ, CPZ, and PPZ.Rate constants are lower in value for PenS., DT.T, DT.E and GuS. radicals of phenothiazines showing that they are dependent upon the structure and the molecular weight of the compound. Rate constants are the same whether the thiyl radicals are generated from thiols or their corresponding disulphides.The k values for chlorine-containing phenothiazines, chlorpromazine, and prochlorperazine are higher than those of promothazine.