Cas 117527-52-3,2',7-disuccinyltaxol

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Check Digit Verification of cas no

The CAS Registry Mumber 117527-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,5,2 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 117527-52:
(8*1)+(7*1)+(6*7)+(5*5)+(4*2)+(3*7)+(2*5)+(1*2)=123
123 % 10 = 3
So 117527-52-3 is a valid CAS Registry Number.

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117527-52-3Relevant academic research and scientific papers

Drug-initiated, controlled ring-opening polymerization for the synthesis of polymer-drug conjugates

Tong, Rong,Cheng, Jianjun

experimental part, p. 2225 - 2232 (2012/06/18)

Paclitaxel, a polyol chemotherapeutic agent, was covalently conjugated through its 2′-OH to polylactide with 100% regioselectivity via controlled polymerization of lactide mediated by paclitaxel/(BDI-II)ZnN(TMS)2 (BDI-II = 2-((2,6-diisopropylph

Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity

Deutsch,Glinski,Hernandez,Haugwitz,Narayanan,Suffness,Zalkow

, p. 788 - 792 (2007/10/02)

Taxol has shown good in vivo antitumor activity in a number of test systems. The formulation of taxol for antitumor testing has been difficult. Esterification at either C-2' or C-7 resulted in loss of in vitro tubulin assembly activity but not cytotoxicit

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