1175536-50-1 Usage
Uses
Different sources of media describe the Uses of 1175536-50-1 differently. You can refer to the following data:
1. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is a useful synthetic intermediate in the synthesis of Efinaconazole; a topical antifungal for onychomycosis. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is also used as a reagent in the synthesis of Ravuconazole; an ergosterol biosynthesis inhibitor and antifungal.
2. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is a useful synthetic intermediate in the synthesis of Efinaconazole (E435070); a topical antifungal for onychomycosis. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is also used as a reagent in the synthesis of Ravuconazole (R128000); an ergosterol biosynthesis inhibitor and antifungal.
Check Digit Verification of cas no
The CAS Registry Mumber 1175536-50-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,7,5,5,3 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1175536-50:
(9*1)+(8*1)+(7*7)+(6*5)+(5*5)+(4*3)+(3*6)+(2*5)+(1*0)=161
161 % 10 = 1
So 1175536-50-1 is a valid CAS Registry Number.
1175536-50-1Relevant articles and documents
A preparation method of the midbody sets up lucky Kang Zuo (by machine translation)
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Paragraph 0037; 0042; 0046, (2017/08/29)
The invention relates to the field of pharmaceutical technology, in particular to a method of preparing intermediates of sets up lucky Kang Zuo, comprising the following steps: D, L - methyl lactate, morpholine, 3, 4 - methoxychroman reaction, with 2, 4 - difluoro bromobenzene reagent reaction to obtain compound III format; compound III in the catalyst under the catalysis of the B L - menthol and triphenylphosphine, by the asymmetric kohl Chaikefusiji reaction to obtain the chiral compound IV; compound IV with 1, 2, 4 - triazole reaction, and then removing the water Cheng Huan, get sets up lucky Kang Zuo key intermediate compound V, this invention uses the D, L - lactic acid methyl ester, by adding the catalyst induction to generate chiral center, greatly reducing the reaction of the raw material cost, high yield, high purity, easy controlled, is suitable for industrial production. (by machine translation)