117559-50-9

Basic information

• Product Name: penta-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate
• Synonyms: penta-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate
• CAS NO: 117559-50-9
• Molecular Weight: 1145.36
• Mol File: 117559-50-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: penta-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: penta-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate(117559-50-9)
• EPA Substance Registry System: penta-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate(117559-50-9)

Safety Data

• Hazardous Substances Data: 117559-50-9(Hazardous Substances Data)

Upstream product

• 117559-40-7 penta-tert-butyl N-benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 117559-43-0 penta-tert-butyl N-(4-aminobenzoyl)-γ-L-glutamyl-γ-L-glutamyl-γ-L-glutamyl-L-glutamate 
• 32816-47-0 penta-tert-butyl N--L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 88443-03-2 L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-glutamic acid pentakis-t-butyl ester 
• 32719-57-6 tetra-tert-butyl N--L-γ-glutamyl>-L-glutamate 
• 73167-55-2 L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamic acid tetrakis-t-butyl ester 
• 32719-56-5 tri-tert-butyl N--L-glutamate 
• 88063-78-9 L-γ-glutamyl-L-glutamic acid tris-t-butyl ester 
• 32677-01-3 L-glutamic acid di-tert-butyl ester hydrochloride 
• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 
• 77766-62-2 2-amino-6-(bromomethyl)-4-hydroxyquinazoline hydrobromide 
• 117559-46-3 penta-tert-butyl N--L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 

Downstream Products

• 117559-54-3 N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamic acid trifluoroacetate salt 

Relevant articles and documents

Quinazoline Antifolates Inhibiting Thymidylate Synthase: Synthesis of Four Oligo(L-γ-glutamyl) Conjugates of N10-Propargyl-5,8-dideazafolic Acid and Their Enzyme Inhibition

The synthesis is described of four oligo(γ-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid containing a total of two, three, four, and five L-glutamic acid residues.The tert-butyl group was chosen as the carboxyl protecting group in