32719-56-5

Upstream product

• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 
• 32677-01-3 L-glutamic acid di-tert-butyl ester hydrochloride 
• 16881-41-7 di-tert-butyl N-Cbz-L-glutamate 
• 34897-61-5 N-(benzyloxycarbonyl)-L-glutamic acid α-t-butyl ester dicyclohexylamine salt 
• 16874-06-9 di-tert-butyl L-glutamate 

Downstream Products

• 32719-57-6 tetra-tert-butyl N--L-γ-glutamyl>-L-glutamate 
• 88050-24-2 tri-tert-butyl N-(4-aminobenzoyl)-γ-L-glutamyl-L-glutamate 
• 117559-42-9 tetra-tert-butyl N-(4-aminobenzoyl)-γ-L-glutamyl-γ-L-glutamyl-L-glutamate 
• 32816-47-0 penta-tert-butyl N--L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 117559-43-0 penta-tert-butyl N-(4-aminobenzoyl)-γ-L-glutamyl-γ-L-glutamyl-γ-L-glutamyl-L-glutamate 
• 32719-58-7 hexa-tert-butyl N--L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 117559-44-1 hexa-tert-butyl N-(4-aminobenzoyl)-γ-L-glutamyl-γ-L-glutamyl-γ-L-glutamyl-γ-L-glutamyl-L-glutamate 
• 117559-53-2 N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamic acid trifluoroacetate salt 
• 117559-41-8 hexa-tert-butyl N-benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 117559-54-3 N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-γ-glutamyl>-L-glutamic acid trifluoroacetate salt 
• 117581-21-2 tri-tert-butyl N--L-γ-glutamyl>-L-glutamate 
• 117559-38-3 tri-tert-butyl N-benzoyl>-L-γ-glutamyl>-L-glutamate 
• 117559-45-2 tetra-tert-butyl N--L-γ-glutamyl>-L-γ-glutamyl>-L-glutamate 
• 117559-48-5 tri-tert-butyl N-prop-2-ynylamino>benzoyl>-L-γ-glutamyl>-L-glutamate 

Relevant academic research and scientific papers

PROCESSES OF PREPARING POLYGLUTAMATED ANTIFOLATES AND USES OF THEIR COMPOSITIONS

Provided herein are methods of preparing polyglutamated compounds, such as polyglutamated antifolates, and/or pharmaceutical compositions such as liposomal compositions comprising the same, Also provided herein are substantially pure polyglutamated compou

Quinazoline Antifolates Inhibiting Thymidylate Synthase: Synthesis of Four Oligo(L-γ-glutamyl) Conjugates of N10-Propargyl-5,8-dideazafolic Acid and Their Enzyme Inhibition

The synthesis is described of four oligo(γ-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid containing a total of two, three, four, and five L-glutamic acid residues.The tert-butyl group was chosen as the carboxyl protecting group in