117601-24-8Relevant academic research and scientific papers
Synthesis of 4-alkyl(aryl, hetaryl)-2-thioxo-5,6,7,8-tetrahydroquinoline-3- carbonitriles and their derivatives by cross-recyclization of 4-alkyl(aryl, hetaryl)-2,6-diamino-4H-thiopyran-3,5-dicarbonitriles with 4-(cyclohex-1-en-1- yl)-morpholine, alkyl halides, and cyclohexanone
Dyachenko,Dyachenko
, p. 412 - 420 (2008/12/22)
Cross recyclization of 4-substituted 2,6-diamino-4H-thiopyran-3,5- dicarbonitriles with 4-(cyclohex-1-en-1-yl)morpholine, alkyl halides, and cyclohexanone gave the corresponding substituted 2-thioxo-1,2,5,6,7,8- hexahydroquinoline-3-carbonitriles, 2-alkylsulfanyl-5,6,7,8-tetrahydroquinoline- 3-carbonitriles, 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2- carboxamides, and 4-oxo-2,2-pentamethylene-1,2,3,4,7,8,9,10- octahydropyrimido[4′,5′:4,5]thieno[2,3-b]quinolines. The structure of 3-(4-bromophenyl)-2,2-pentamethylene-11-(2-thienyl)-1,2,3,4,7,8,9,10- octahydropyrimido[4′,5′:4,5]thieno[2,3-b]quinoline was proved by X-ray analysis.
Rearrangement Studies on Cycloalkylidene Ring Systems: Differences Between the Reactions of Cycloalkanone Oximes and Cycloalkylidenemalononitriles with Arylmethylidene(cyano)thioacetamides
Elgemeie, Galal E. H.,Alnaimi, Ibrahim S.,Gawad, Mona A.
, p. 424 - 433 (2007/10/02)
A novel synthesis of condensed pyridine-2(1H)-thiones utilizing cycloalkanone oximes and arylmethylidene(cyano)thioacetamides as starting components is described.
