117607-12-2Relevant articles and documents
Asymmetric intramolecular hydroamination of alkenes in mild and wet conditions - Structure and reactivity of cationic binuclear gold(I) catalysts
Abadie, Marc-Antoine,Trivelli, Xavier,Medina, Florian,Capet, Frederic,Roussel, Pascal,Agbossou-Niedercorn, Francine,Michon, Christophe
, p. 2235 - 2239 (2014)
A selected diphosphine binuclear gold(I) chloride complex was combined with a silver salt to catalyze efficiently, for the first time, the asymmetric intramolecular hydroamination of alkenes with high conversions and enantioselectivities, in mild conditions and in presence of water. Both enantiomers of the products could be obtained by controlling the molecular ion-pairs through the solvent polarity. The gold(I) cationic active species was characterized unambiguously at the solid state by X-ray analysis and in solution by DOSY 1H NMR experiments. No contribution of silver chloride was observed on the bonding mode of the catalyst.
Catalytic Reduction of Alkyl and Aryl Bromides Using Propan-2-ol
Haibach, Michael C.,Stoltz, Brian M.,Grubbs, Robert H.
supporting information, p. 15123 - 15126 (2017/11/20)
Milstein's complex, (PNN)RuHCl(CO), catalyzes the efficient reduction of aryl and alkyl halides under relatively mild conditions by using propan-2-ol and a base. Sterically hindered tertiary and neopentyl substrates are reduced efficiently, as well as more functionalized aryl and alkyl bromides. The reduction process is proposed to occur by radical abstraction/hydrodehalogenation steps at ruthenium. Our research represents a safer and more sustainable alternative to typical silane, lithium aluminium hydride, and tin-based conditions for these reductions.
Stereochemical aspects of the 'tert-amino effect'. 2. Enantio- and diastereoselectivity in the synthesis of quinolines, pyrrolo[1,2-a]quinolines, and [1,4]oxazino[4,3-a]quinolines
Nijhuis,Verboom,Abu El-Fadl,Van Hummel,Reinhoudt
, p. 209 - 216 (2007/10/02)
-