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(S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE, a pyrrolidine derivative with the molecular formula C13H18ClNO2, is a chemical compound featuring a chloromethyl group and a carboxybenzyl (CBZ) protective group. (S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE is recognized for its unique structure and reactivity, making it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. Its role as a chiral auxiliary in asymmetric synthesis further enhances its utility in controlling the stereochemistry of new chemical compounds, with potential applications in medicine and agriculture.

61350-66-1

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61350-66-1 Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE is used as a building block for the creation of various pharmaceuticals due to its unique structure and reactivity. It contributes to the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Synthesis:
In the agrochemical industry, (S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE serves as a key component in the synthesis of new agrochemicals, potentially leading to the development of more effective and environmentally friendly pesticides and herbicides.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
(S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE is utilized as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of chemical compounds. This application is crucial for the production of enantiomerically pure compounds, which are essential in various fields, including medicine, where the stereochemistry of a molecule can significantly impact its biological activity and safety.
Used in Research and Development:
(S)-1-N-CBZ-2-CHLOROMETHYL-PYRROLIDINE's unique properties make it a valuable tool for researchers in the fields of organic chemistry and medicinal chemistry. It is used for exploring new reaction pathways, developing innovative synthetic methods, and understanding the fundamental principles of stereoselective synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 61350-66-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,5 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 61350-66:
(7*6)+(6*1)+(5*3)+(4*5)+(3*0)+(2*6)+(1*6)=101
101 % 10 = 1
So 61350-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H16ClNO2/c14-9-12-7-4-8-15(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2/t12-/m0/s1

61350-66-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name benzyl (2S)-2-(chloromethyl)pyrrolidine-1-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61350-66-1 SDS

61350-66-1Relevant academic research and scientific papers

Gold(I)-catalyzed enantioselective intramolecular dehydrative amination of allylic alcohols with carbamates

Mukherjee, Paramita,Widenhoefer, Ross A.

supporting information; experimental part, p. 1405 - 1407 (2012/03/11)

Aliphatic nitrogen heterocycles either five- or six-membered are formed in high yield and with up to 94 %ee when a 1:2 mixture of [(S)-2](AuCl)2 and AgClO4 is used as the catalyst for the title reaction. Copyright

A new class of potent non-imidazole H3 antagonists: 2-Aminoethylbenzofurans

Cowart, Marlon,Pratt, John K.,Stewart, Andrew O.,Bennani, Youssef L.,Esbenshade, Timothy A.,Hancock, Arthur A.

, p. 689 - 693 (2007/10/03)

2-Aminoethylbenzofurans constitute a new class of H3 antagonists that are more rotationally constrained than most previously reported H3 antagonists. They retain high potency at human and rat receptors, with efficient CNS penetration observed in 35. The SAR of the basic amine moiety was compared in three different series of analogues. The greatest potency was found in analogues bearing a 2-methylpyrrolidine, a 2,5-dimethylpyrrolidine, or a 2,6-dimethylpiperidine.

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