117609-27-5

Upstream product

• 106-88-7 ethyloxirane 
• 62-53-3 aniline 
• 96-20-8 2-aminobutanol 
• 591-50-4 iodobenzene 
• 108-86-1 bromobenzene 
• 117609-26-4 (S)-(+)-2-phenylamino-3-butenol 
• 103-71-9 phenyl isocyanate 
• 117609-19-5 4-vinyl-3-phenyl-2-oxazolidone 

Relevant academic research and scientific papers

A magnetic nanoparticle-catalyzed regioselective ring opening of epoxides by aromatic amines

Sulfonic acid-functionalized silica-coated magnetic Fe3O4 nanoparticles were synthesized and applied as a green catalyst for an efficient and environmentally friendly ring opening of epoxides with aromatic amines in good to excellent

Graphite oxide catalyzed synthesis of β-amino alcohols by ring-opening of epoxides

Graphite oxide as a heterogeneous and recyclable solid acid catalyzed a simple and efficient method for the synthesis of β-amino alcohols by ring opening of epoxides with amines. This method is effective with various aromatic and aliphatic amines under solvent-free conditions. The corresponding β-amino alcohols are obtained in high yields (56%-95%) and short reaction times (15-30 min) with high regio- and chemoselectivity under metal-free conditions.

Substrate-promoted copper-catalyzed N-arylation of amino alcohols with aryl iodides in water

An efficient method has been developed for the N-arylation of a variety of water-soluble amino alcohols (1.2 mmol) with aryl iodides (1.0 mmol) in water under CuI-catalyzed conditions. The reaction was conducted via substrate-promoted action and did not require an additional ligand or phase-transfer catalyst, and afforded the desired N-aryl amines in acceptable to excellent yields (64%-93%) under mild reaction conditions with a small excess of the amino alcohol.

Catalyst-free regioselective ring opening of epoxides with aromatic amines in water and solvent-free conditions

Without using any catalysts, a variety of epoxides undergo ring-opening by aromatic amines to afford the corresponding 1,2-amino alcohols in high to excellent yields with good regioselectivity in the presence of water as solvent and under solvent-free con

Solvent-free copper-catalyzed N-arylation of amino alcohols and diamines with aryl halides

A simple and mild method for the coupling of aryl halides with amino alcohols and diamines is described. The reactions can be performed under ligand-free and solvent-free conditions, and generate the products in good yield.

Hβ zeolite: An efficient and reusable catalyst for ring-opening of epoxides with amines under microwave irradiation

A solvent-free protocol for the synthesis of β-amino alcohols (Yield, up to 94%) is demonstrated by the ring-opening reactions of meso and terminal epoxides with aromatic amines using Hβ zeolite as catalyst under microwave irradiation. The catalytic syste

Highly efficient ring opening reactions of epoxides with deactivated aromatic amines catalyzed by heteropoly acids in water

Heteropoly acid was found to be an effective and efficient catalyst for the ring opening reaction of epoxides with various aromatic amines to produce the corresponding β-amino alcohols in moderate to excellent yields in water. This method provides a new and efficient protocol in terms of mild reaction conditions, clean reaction profiles, small quantity of catalyst, and simple work-up procedure.

Aluminium triflate: an efficient recyclable Lewis acid catalyst for the aminolysis of epoxides

Epoxides are powerful starting materials for a range of useful materials and can be converted into, amongst others, amino alcohols. In this work, a range of epoxides was ring-opened using various alkyl- and arylamines under the action of aluminium triflat

Decomplexation of (η-Arene)(η-cyclopentadienyl)iron(II) Hexafluorophosphates: a Convenient One-pot Arylation Procedure

A study has been made of the relative merits of range of decomplexation reagents in the demetallation of salts. 1,8-Phenanthroline have good yields of the free ligand when simple arene complexes were used but did not demetallate more sterically hindered species.The reaction was found to be light sensitive.Bipyridine gave much lower yields.Potassium tert-butoxide in pyridine or DMSO was found to be an excellent demetallating agent even with sterically crowded complexes.A one-pot arylation procedure was developed and extended to include a number of important heterocyclic derivatives.The mechanism of these decomplexation reactions is briefly adressesd.

ASYMMETRIC CYCLIZATION OF 2-BUTENYLENE DICARBAMATES CATALYZED BY CHIRAL FERROCENYLPHOSPHINE-PALLADIUM COMPLEXES: CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE 2-AMINO-3-BUTENOLS

Cyclization of 2-butenylene dicarbamates (RNHCOOCH2CH=CHCH2OCONHR: R = Ph, MeOC6H4, PhCH=CH, etc.) in the presence of a palladium catalyst coordinated with chiral (hydroxyalkyl)-ferrocenylphosphine ligand gave optically active 4-vinyl-2-oxazolidines (up t